Can anyone share their experience with Pluvicto?

@waldipup, I'm sorry that your good deed for your friend is causing you concern.

With you and your friend being separated between the front seat and him diagonally behind you in the back seat, your distance will met or exceeded the required 3 feet and your time together was limited to 2 hours. The recommendation is to LIMIT close contact (less than 1 meter or 3 feet).

This is the same recommendation for men and women. However, extra precautions are suggested for pregnant women and children.

Thank you for your kindness and offering to drive your friend. I'm sure it was a great comfort to him to not have to drive himself. This is a time when he needs friends like you.

I don't put much faith in what the radiation doctors have to say about the radiation issues .
They released him with no warnings regarding a possible cab driver (or in my case , friend driver) , and being in Manhattan , he very likely could have taken a bus or train at rush hour pressed against others for periods of time .

So they're not too focused on that issue . And I don't think they know for sure just where "dangerous" ends and "ok" begins anyway , it's kinda an uncertainty .

First of all, the usual "medical disclaimer". I am not a doctor. This is a question you should pose to the radiation doctor.

Having said that, I can tell you my personal experience.

With you driving and him sitting diagonally in the back seat you are about three feet away from each other. They turn you loose from the Pluvicto administration when your radiation level is around three. Radiation exposure is cumulative so during the two hour drive you are getting about a six - not great but in my opinion nothing to be particularly concerned about.

I live about an hour and a half drive from my treatment center. I too have minimal side effects from the treatment. As such. I drive myself to and from the treatment in order to minimize me exposing anyone else.

After treatment. I completely isolate myself for one week based on my declining radiation levels. They tell you to isolate at least three feet for three days, but I am personally not comfortable that that is sufficient for my tastes. I then restrict my close contact for a second week (no sleeping together, brief hugs or handshakes ok but no prolonged physical contact etc.) After those two weeks my radiation level is negligible so all contact is fair game.

Since your friend also has minimal side effects, is there any reason he couldn't drive himself?

First of all, the usual "medical disclaimer". I am not a doctor. This is a question you should pose to the radiation doctor.

Having said that, I can tell you my personal experience.

With you driving and him sitting diagonally in the back seat you are about three feet away from each other. They turn you loose from the Pluvicto administration when your radiation level is around three. Radiation exposure is cumulative so during the two hour drive you are getting about a six - not great but in my opinion nothing to be particularly concerned about.

I live about an hour and a half drive from my treatment center. I too have minimal side effects from the treatment. As such. I drive myself to and from the treatment in order to minimize me exposing anyone else.

After treatment. I completely isolate myself for one week based on my declining radiation levels. They tell you to isolate at least three feet for three days, but I am personally not comfortable that that is sufficient for my tastes. I then restrict my close contact for a second week (no sleeping together, brief hugs or handshakes ok but no prolonged physical contact etc.) After those two weeks my radiation level is negligible so all contact is fair game.

Since your friend also has minimal side effects, is there any reason he couldn't drive himself?

Hi redro . First off wishing you the best results , my friend so far had 2 P treatments , feels great and no side effects .
My concern is that I'd picked him up immediately following his first treatment and it was a 2 hour ride to get him home with the car windows closed and he in the back seat diagonally behind me .
I see that you are well versed in exposure issues and wonder if you feel that I may have been affected by my immediate , enclosed , proximate 2 hour contact?

For those following my Pluvicto treatment, my personal protocol and why, I am now two weeks after my fourth Pluvicto radiation infusion.

My current radiation readings are:

Arms length (3 feet): 0.01

One foot away: 0.03

Next to body: 0.22

If you recall, they turn you loose from the hospital when your 3 foot reading is around 3.

So my personal experience as above shows a decline in my 3 foot measurement from a 3 to a negligible 0.01.

With my next to body reading having declined to 0.22 I now deem myself to be relatively safe to be with people and to have extended contact.

My concern on all of this is to NOT cause "collateral radiation damage" to any caregivers, friends and loved ones. The cumulative level of damage through exposure is the strength of the radiation times the amount of time exposed. At my current next to body reading of 0.22 millirems per hour a person who was in constant contact with me for one hour would receive only 0.22 millirems of radiation. This may be compared to the standard cumulative radiation limit level of 100 millirems per year.

To summarize, my personal protocol is to isolate myself completely for one week, to allow casual, but no extended contact for the second week after treatment, and to resume "normal" life thereafter until my next treatment which comes in four more weeks if thete are no complicating factors.

Hope this information has been useful to those who are interested in a deeper dive into the effect of Pluvicto treatments on their body as it relates to radiation exposure to caregivers, friends and family.

To Baxterlee77:

Until fairly recently it WAS FDA protocol that if you had not already had chemotherapy you could not get the Pluvicto treatment. I WANTED the Pluvicto treatment but was denied due to me (by my choice) NOT having had chemotherapy.

This restriction began to be grudgingly lifted around December 2023 when I was able to start Pluvicto treatment without having had chemotherapy.

If you WANT Pluvicto, but are still being told by your oncologist that you can't get it if you haven't had chemotherapy, he is simply not up to date on the current restrictions. This is from my personal experience where I tried to receive the Pluvicto treatment for several months, was denied treatment due to FDA restrictions saying I had to have had chemotherapy first, and then having that restriction lifted so that I could begin receiving the Pluvicto treatment last December.

Thanks for the hugs!

An update. Since the pain is not well controlled I had another bone scan and CT with contrast. As I read the results, the Pluvicto isn't working well for me and the cancer may still be slowly spreading. I see my oncologist next week for a more thorough explanation.

Thanks for the hugs!

An update. Since the pain is not well controlled I had another bone scan and CT with contrast. As I read the results, the Pluvicto isn't working well for me and the cancer may still be slowly spreading. I see my oncologist next week for a more thorough explanation.