Cabozantinib Response: Initial Shrinkage, Now Stable – Is This Normal?

My mom has been undergoing treatment for kidney cancer since December 2024 with Cabozantinib 40mg. After completing two bottles, a CT scan in March showed that several nodules had shrunk or even disappeared — a clear sign the medication was working.

She continued on another two bottles of Cabozantinib 40mg, and we repeated the CT scan this July (4 months later). This time, the results showed that the nodules remained stable, with no further shrinkage. One nodule even increased slightly by about 2mm.

Has anyone else experienced something similar? Is it normal for nodules to remain stable or slightly increase during treatment, even if there was a good response early on?

Also, does anyone know of the best kidney cancer specialists in the U.S.?