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Ca 27-29 for early breast cancer
Hello everyone,
I am scared about my last Ca 27-29 resukts for early breast cancer, and would like to hear your experience with this marker.
This month, the result measured at Quest lab by my doctor was 51 U/ml (upper normal limit 38). The same day I also had it tested at Quest independently (as I thought my doctor didn’t order it) and the result was 40 U/ml, still a little high, but better (same day, different blood sample).
Last month it was 38. Before that, we used to measure the Ca 15-3, and while it had gone from 24 to 28 lately, it also went back to 25 last month. This month my doctor has not ordered the ca 15-3.
I am very scared. I was diagnosed a year ago with er+pr+Her2-, low oncotype (10), low Ki-67 (4%) multi focal breast cancer with biggest focus 8 mm, one involved lymph node. I am currently on Lupron, exemestane and Kisqali. Given the low oncotype I thought, if I had to have a recurrence along the way, it would be in many years. I can’t stop thinking that I have distant metastasis now, and it’s Saturday today, so there’s no one to talk to. Please share your experience, thank you very much
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Hello @arianna83, I know this is distressing to you but try not to make yourself crazy over the weekend.
As you know since you were diagnosed before, a couple days makes no difference in the diagnosis or the treatment. If there is actually a diagnosis at all.
My doctor saw my tumor markers going up and down so drastically he really wanted me to see a new oncologist, but the one I had was amazing and said he only orders them to see trends since the are pretty unreliable as immediate predictors. When he saw them going up each time he checked for multiple months, then he ordered a scan.
You mentioned that you were on lupron, Exemestane, and kisqali, are you still treating the original diagnosis, or is this a lot of preventative treatment?
Thank you for your reply Chris, yes, Lupron, Exemestane and Kisqali are still for the original diagnosis, stage 2a early breast cancer. Did you say that it happened to you as well to have these markers go up for reasons other than recurrence? It just seems very unlikely to have a recurrence after just about a year with my low oncotype. I attribute it to Kisqali, which has effects similar to chemotherapy, but couldn’t find anything online. Thank you for your encouragement
I am on Anastrozole for 2a early breast cancer also.
After reading your post, arianna83, I am now wondering if I should be on your medication regimen.
To be honest, I don't know exactly what Lupron or Kisqali is or does.
I will research it. Thank you for your input.
My oncologist also does the 27-29 and has since we started. I had surgery (high Ki67 and positive oncotype), chemo and radiation. Went onto anastrazole and now on exemestane. Mine went from 90, bounced around then to 69 after chemo. Stayed there for 4 months then started going up - 75 to 83 to 87 - at which point he ordered pet scan and brain imaging. Both negative and it suddenly dropped back to 69 after 6 months on ai. Has since dropped to 59 and has now been sitting there between 52 and 59 for almost a year. Some people apparently never go back to normal and they don’t know why. However he’ll continue to monitor every 3-6 months unless something changes drastically. So don’t over worry it. Your doctors still keeping an eye one it and there can be fluctuations that mean nothing.