Brinsupri Side Effects: Anyone have double vision?

I’ve been on brensocatib for a little over 3 months. Today I’m in the hospital being evaluated for a possible TIA of my right eye. This is what happened in a nutshell: I was standing in my house waiting to go for an endoscopy to help determine how bad my reflux is and if it may have caused my bronchiectasis. Suddenly a curtain seemed to descend over my right eye and my brain went fuzzy. Only lasted for 10 seconds or so and all symptoms disappeared. Foolish me, I went for the endoscopy but later in the day I got to thinking about my eye so went to the ED. I’ve been here 4 days now getting various tests. Still don’t know anything.

Is it related to the brensocatib? I don’t know. I’m calling Insmed tomorrow to discuss it with them.

@coffcoff
Have they checked for retinal detachment also? The sudden "curtain over your eye" is a main symptom of that as well as a blockage of blood flow to the retina (TIA).

@cwal Yes, I had a very thorough exam by an ophthalmologist before I was discharged from the hospital. Everything looked fine with my eyes, thank God. Best guess is I had a transient ischemic episode of my eye. I'll let y'all know what Insmed says, though I suspect it had nothing to do with the bresocatib.