I had my Botox injection yesterday in my LES. They say it went well. It is too early to say if it helps tho it does seem to. I was very sick yesterday afternoon and evening, pain, nausea and heartburn. I woke up at 4 AM with very bad heartburn and a little vomiting. I am doing better today. I was told I would have increased heartburn. Just have to learn how to control it. I already take Nexium, Mylanta and Gas Ease. I will report back in a few weeks on how it is working.