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Blessed Thistle with positive results?
Has anyone tried Blessed Thistle (Cnicus Benedictus) with positive results? I've just read an article in ScienceDaily Titled "New Compound From Blessed Thistle Promotes Functional Nerve Regeneration" dated April 19, 2024 Source: University of Cologne stating that a novel new use for Cnicus has been found. Animal studies as well as human cells have shown that Cnicin significantly accelerates Axon (nerve fiber) growth.
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I will say it is probably not worth running out and just taking the supplement. From the article
“The correct dose is very important here, as Cnicin only works within a specific therapeutic window. Doses that are too low or too high are ineffective”
https://www.sciencedaily.com/releases/2024/04/240419182009.htm-
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5 ReactionsI also found the full paper here: https://www.sciencedirect.com/science/article/pii/S0944711324003003
They were testing against nerve injury and not neuropathy so not sure how applicable it is for us.
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6 ReactionsI hear what your are saying. With that said, I put it out here b/c someone on another support group with diabetic PN brought it forward claiming it has helped to regain sensation in his feet. So I was interested to hear if others have used this for PN and their experience. Positive or Negative. Thanks!
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3 ReactionsWelcome to Mayo Clinic Connect. You will find so many people willing to share their experiences.
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2 ReactionsCan't neuropathy be the result of nerve injury?
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3 ReactionsAbsolutely neuropathy can be the result of nerve injury...
"Peripheral neuropathy happens when the nerves that are located outside of the brain and spinal cord (peripheral nerves) are damaged. This condition often causes weakness, numbness and pain, usually in the hands and feet. It also can affect other areas and body functions including digestion and urination."
--- https://www.mayoclinic.org/diseases-conditions/peripheral-neuropathy/symptoms-causes/syc-20352061
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2 ReactionsThis was very interesting and encouraging. I have axonal peripheral neuropathy with kappa light-chain MGUS. Waiting 6 months for my next set of routine tests is pretty anxiety-producing as the neuropathy continues to progress. It started in the soles of my feet and toes in July 2023 and now goes above the knees in both legs, sometimes mildly up my thighs. So I'm not thrilled about waiting for blood tests to confirm - what? LC-MGUS? We already know that.
But maybe there will be a treatment to help repair axonal damage, especially if the source of the damage can also be quashed.
(I seem to be an anomaly with LC-MGUS and PN. But other potential causes of neuropathy were ruled out.)
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2 ReactionsPeople here with physical nerve damage due to trauma in their spine will experience neuropathy. On my MRI reports they mention arachnoiditis and stenosis. Has anyone here had that diagnosis and then had a spine surgeon correct those conditions? If so did that reduce or eliminate the assocated neuropathy? Is it possible to fix arachnoiditis and stenosis with a minimaly invasive procedure?
It might be something to discussion with your care team. There are some members that have posted about arachnoiditis, stenosis and surgery. Here's a link showing the member comments - https://connect.mayoclinic.org/search/?search=arachnoiditis+%2Bstenosis+%2Bsurgery
So, why is it that some with neuropathy complain of tingling and numbness, but not pain? I would gladly trade my pain (anywhere between 7-9 now) for tingling and numbness. Riddle me that.