Baclofen for Chemo-induced Peripheral Neuropathy?

Posted by nodunk @nodunk, Aug 27 4:58pm

Trying this for Chemo Induced Peripheral Neuropathy. Approved for Multiple Sclerosis. Primary care doc thought it was worth a try. Duloxetine didn’t help as it does for some. Anyone else using Baclofen for pain?

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Hi @nodunk, We expanded your discussion title so that others will know what your dicussion is about and be able to share their experience with you. I don't have pain with my PN but have tried many topicals with little to no success for helping the numbness and tingling in my feet and legs. If I remember correctly you have tried lot of different treatments and done a lot of research which is good. Hopefully it will provide some relief for you.

Most of the articles I've found mentioned baclofen in a topical containing baclofen, amitriptyline and ketamine. Is the baclofen part of a topical prescribed by your doctor or is it an over the counter product?

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My understanding is that Baclofen affects the central nervous system. Medications like Gabapentin are used more for peripheral neuropathy. My doctor has me on a small dose of Baclofen for muscle spasms. It has helped. She wants to up my dose and I probably will before too long.

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Hi @nodunk
I also have chemotherapy induced neuropathy, i have been taking baclofen for Trigeminal Neuralgia pre-chemotherapy, and therefore pre neuropathy. It does nothing for the neuropathy. I have used cold laser therapy for neurapathy and that had worked for the most part. (There are just so many other issues…)
I try to do every day:
Yoga (Happy feet yoga on youtube), myofascial massage, roll with a tiger tail and a hard ball, and I exercise. I was bitten by a tick last week and my neuropathy went full out pain. It has calmed down, but not to where it was. I can not do as much as I did until the rash from lyme disease calms down. I hope my IVig helps that heal faster along with everything else it does.

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You are a trooper! Baclofen was a shot in the dark for my CIPN. I believe Neurofeedback if I can ever get it is the answer. Try water aerobics. I usually get 6 hours of relief after using the pool early every morning.

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I’ve been taking oral Baclofen for over 20 years as an antispasmodic for my back and leg spasms. It has been beneficial in my opinion, although I still get periodic spasms but tolerable. I never had any expectations of complete relief but I’m good.

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