Avastin for maintenance

Posted by marfish @marfish, Mon, Jul 15 2:21pm

I’m new to the group. I’m starting treatment for first recurrence to include Carbo/Taxol/Avastin, after which I’m supposed to continue Avastin as maintenance. Hoping to hear how this has worked for others. Thank you.

Welcome to Connect, @marfish. I'm tagging @miyonggilman @7429 @starko @mommyjeanne3 and @pat417 on this discussion because they each have experience with bevacizumab (Avastin).

Marfish, what type/stage of cancer do you have?

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@colleenyoung

Welcome to Connect, @marfish. I'm tagging @miyonggilman @7429 @starko @mommyjeanne3 and @pat417 on this discussion because they each have experience with bevacizumab (Avastin).

Marfish, what type/stage of cancer do you have?

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Thank you. I was diagnosed 3C ovarian originating in fallopian. I’m brca negative.

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@marfish

Thank you. I was diagnosed 3C ovarian originating in fallopian. I’m brca negative.

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Hi @marfish. I also had 3C ovarian, carbo/taxol, but not Avastin. Also, BRAC negative. I went through the usual surgeries, IV & IP chemos and am currently on metformin. It has been almost 3 months since my last chemo and so far, the cancer has not reappeared. I need to add that I am on a metabolic life style; Mediterranean diet, exercise, meditation, 16 hour fast 5 days/week, all the fun things!

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@starko

Hi @marfish. I also had 3C ovarian, carbo/taxol, but not Avastin. Also, BRAC negative. I went through the usual surgeries, IV & IP chemos and am currently on metformin. It has been almost 3 months since my last chemo and so far, the cancer has not reappeared. I need to add that I am on a metabolic life style; Mediterranean diet, exercise, meditation, 16 hour fast 5 days/week, all the fun things!

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Thank you. What is a metabolic lifestyle?

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@marfish

Thank you. What is a metabolic lifestyle?

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Hi. Basically, a very healthy life style: Mediterranean diet, exercise, meditation, massages, 16 hour fast 5 days/week and relaxation

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@starko

Hi. Basically, a very healthy life style: Mediterranean diet, exercise, meditation, massages, 16 hour fast 5 days/week and relaxation

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Forgot to mention the most important aspect of my regime is absolutely NO SUGAR! It has been proven that sugar feeds cancer and some clinicals indicate that sugar can cause cancer. Also, no processed carbs. Hope that helps!

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My 1st, 2nd, 3rd, and 5th treatment was (carbo, taxol, avastin); I have one more treatment (not certain if avastin will be included); My team suggested, avastin for maintenance; Whats the minimum length of time before reoccurrence appears?

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@pbprice

My 1st, 2nd, 3rd, and 5th treatment was (carbo, taxol, avastin); I have one more treatment (not certain if avastin will be included); My team suggested, avastin for maintenance; Whats the minimum length of time before reoccurrence appears?

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My understanding is that if cancer returns within six months of chemo, the cancer is considered resistant to platinum based chemotherapy. If the cancer takes longer than six months to recur, it is considered platinum sensitive. Those who have platinum sensitive cancer retain the possibility of receiving another round of platinum based chemo, or sometimes a second surgery. Those with platinum resistant cancers have other drug options, like PARP inhibitors.
Be sure to continue testing CA125 and HE4,S for a rise in either one. If there are three consecutive rises in either, even if within the normal range, a CT scan should be called for.
And, try to follow all the good health directions your doctor gives you.
I am currently on metformin and beginning my 6th month without recurrence.
Hoping and praying!

Liked by Pamela

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@starko

My understanding is that if cancer returns within six months of chemo, the cancer is considered resistant to platinum based chemotherapy. If the cancer takes longer than six months to recur, it is considered platinum sensitive. Those who have platinum sensitive cancer retain the possibility of receiving another round of platinum based chemo, or sometimes a second surgery. Those with platinum resistant cancers have other drug options, like PARP inhibitors.
Be sure to continue testing CA125 and HE4,S for a rise in either one. If there are three consecutive rises in either, even if within the normal range, a CT scan should be called for.
And, try to follow all the good health directions your doctor gives you.
I am currently on metformin and beginning my 6th month without recurrence.
Hoping and praying!

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Thanks! Very good info, I had no knowledge of

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