As promised, my successful tapering off Effexor (Venlafaxine)
Below you will find the tapering plan that I used to successfully wean myself off Effexor (Venlafaxine). Feel free to share this with your doctor If you would like. I researched and came up with this plan, which was approved by my doctor, although she thought I could probably have weaned myself off sooner. But the reality is that we all have differing tolerance levels for tapering and weaning off this powerful drug from our bodies. Some people can taper faster, but usually not those who have been on this drug for years (like myself, since October 2002). I tapered off EffexorXR 150mg capsules about 5 years ago down to 75mg, and was on that maintenance dosage for a couple of years until I started weaning off the 75mg a year ago in April 2019. As of October, 2029, I’ve been withdrawal symptom free, but I still have occasional periods of anxiety when triggered. But I realize these waves of anxiety will soon pass, and I cope by deep breathing, taking a walk, having a cup of chamomile tea, etc. Cutting my exposure to watching upsetting news has really helped a lot as well. These days I seek things that bring joy and peace in such a turbulent world. Wishing you all a successful weaning off this powerful drug.
Weaning off Venlafaxine XR 75mg (Effexor-(extended release)capsules:
Weaning plan off plan that worked for BSS:
1. Inform your doctor you are tapering down from 75 mg Venlafaxine and ask them to prescribe 37.50 tabs to help with tapering doses (1/2 dosage down from 75 mg Venlafaxine capsules). The tabs are easier to cut into halves and quarter dosages than counting out beads from the capsules.
2. Begin your taper only after you are on a non-withdrawal symptomatic dosage level. If you were having w/d symptoms at 75 mg, you’ll need to go back to the level at which you were symptomless and stay there for 2-3 weeks before deceasing to a slow taper. NOTE: after successfully tapering from 150mg Venlafaxine down to 75mg for a month, I was unable to tolerate a drop cold turkey from a daily dosage of 75mg down to 37.50mg (50%) without having bothersome withdrawal symptoms of dizziness, brain fog, brain zaps, and nausea. So after researching various tapering plans, I came up with a slower tapering schedule my body could tolerate to finish the tapering from 75mg to 37.50mg, and then on to complete the tapering. Your body may even need slower tapering, so adjust according.
3. Week 1-2: Take 75mg caps MWFSu; take 37.50mg tab on alternate days Tu,Th, Sa. At the end of week 2, if you only have relatively mild to no withdrawal symptoms, proceed to week 3. IMPORTANT: If you have intolerable symptoms, adjust to a slower tapering schedule by adding an additional 1/2 tab on the alternate days (or take a total of one and a half 37.50 tabs on alternate days). You’ll then have to tweak the rest of your tapering schedule. If all goes well, proceed with week 3.
4. Week 3-4: Cut a few 37.50 tabs in half with a pill cutter or exacto knife blade to create quarter pieces. Take 37.50mg tab on MWFSu and take 3/4 tab on alternate days Tu, Th, Sa.
5. Week 5-6: Take 3/4 of a tab MWFSu, and take 1/2 tab on alternate days Tu, Th, Sa. If only mild symptoms, proceed to week 5.
6. Week 7-8: Take 1/2 tab on MWFSu; and take 1/4 tab on alternate days Tu, Th, Sa. If no symptoms, continue to week 7.
7. Week 9-10: Take 1/4 tab on MWFSu; and take 1/8 tab (cut 1/4 tabs in half) on alternate days Tu, Th, Sa. *Notice the quartering of doses into crumbs now...very important to keep small dosage tapering to remain withdrawal symptom free.
8. Week 11-12: Take 1/8 tab crumb on MWFSu; take none on alternate days Tu, Th, Sa. *If skipping alternate days produces symptoms, stay on 1/8 tab crumbs for a couple of weeks before alternating skip days for a couple of weeks.
You’ll find that this schedule may have to be tweaked for you by extending the time you stay on a taper...possibly up to 3-4 weeks before beginning a new tapering down. It all depends on how you tolerate the first two weeks.
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@sears
Yes it does with a siringe that fits in the cap of the liquid bottle and you turn the bottle upside down and draw the liquid into the siringe. It doesn't leak.
It is easier to taper the medicine that way and that's what I got it for.
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1 Reaction@michelle73 I don’t know why doctors don’t use the liquid more. Much easier than messing with beads.
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1 Reaction@goodheartmom Since he has been taking the drug for months and not years, his prospects of discontinuing successfully are better. Generally, the lower the dose and the less time on the drug, the lesser the side effects from withdrawal. That said, everyone is different and your husband has other issues, possibly other medications?
There is a tremendous amount of information on this website--yes, it would take a long time to read it all; you would learn a lot in the process and might be able to work out a solution for yourself. Another excellent resource is The Maudsley Deprescribing Guidelines, a book published 2024 by Mark Horowitz and David Taylor. Mark Horowitz/Outro has a lot of information online to aid one in discontinuing this drug successfully.
I would suggest you speak with your pharmacist. Effexor is available in 37.5 mg capsules (extended release, taken once a day), and in 25 mg tablets (immediate release, taken twice a day). My independent pharmacist was able to create a liquid form which I take twice a day and is simple to reduce over time. It is possible, albeit tedious, to open the capsules and reduce the contents by a fraction. My pharmacist helped me learn how to do this and provided empty capsules, a tiny lipped tray and a funnel for refilling capsules. It is also possible to use a pill cutter to cut the tablets into reduced doses over time. An independent pharmacist could create a liquid for you, but compounds are not typically covered by insurance.
Learn as much as you can and create a reduction schedule that best works for you and your husband. If you find that he is decreasing too quickly, then you simply up the dose, whether partially or fully. The main issue I see here is that symptoms of withdrawal (nightmares is one) might mimic your husband's side effects from the drug, and I do not know how you would distinguish between the two.
My heart goes out to you. I am so sorry that you find yourselves in this difficult position--but you CAN do it.
@cjf I sincerely hope you sent my tapering plan off Effexor to your doctor. He obviously wanted to keep you on it as prescriptions are a cash cow and steady income. So he may not give any creedance to a successful weaning off plan, unless he is truly all about supporting your complete healing from taking the most addictive antianxiety/anti depressive in the market. And I think we all know the answer to that question. I was a lucky one who had the support of my Doctor, who offered a plan that tapered too early for me and I had to figure out my own slower “crumb” dosing. I pray you were successful in your deliverance from this evil drug! 🙏💕🙏🙌
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1 Reaction@intendtorecover buspirone 10mg helped me deal with the depression and anxiety and I only needed it a short time to take off the edge from overthinking. It is not addictive and helps greatly. I only take it as needed on occasion, but no longer 3 times a day.
@jules61 I did not gain weight. I actually lost it as I was doing intermittent fasting already due to my late night owl researching of natural remedies.
@effexcausinganxiety I pray your efforts were most successful and you were able to wean yourself off that demonic, addictive drug! 🙏💕🙏🥰🙌
@sears
Yes I actually live in Italy but I got the idea from watching The psychiatrist who works for a psychiatric drug tapering clinic.
I finally got a woman doctor that was more open minded and she prescrived the liquid drug for me in liquid form
@michelle73 I used liquid Valium when tapering off of Xanax. Made the process much easier. Was it Josef Witt-Doering?
My apologies for the error regarding October 2029 when I was symptom free from tapering off Venlafaxine (Effexor). The time period should have been October 2019.