Are you taking Reclast for osteoporosis?

@marythemind
Thank you Mary, so sorry for the pain you're still in yet very happy to hear that you've had no discomfort from the reclast. Posts like yours are very encouraging, tysm.

How much time to you have to wait before switching from Prolia to Reclast? I am due for my Prolia shot on Feb. 17, but I'm switching to Reclast. I made an appointment for my first Reclast infusion on March 13. I was told I needed to wait a few weeks for the Prolia to leave my system before starting on Reclast, but not to wait too long because of Prolia's rebound effect. Does this sound correct?

I thought the standard time was 6 months after the last Prolia shot. And some providers, such as Keith McCormick, suggest using the CTX (and maybe the P1NP) blood test to make sure the timing is right. According to McCormick's book "Great Bones" you need active bone remodeling for Reclast to work. (One of my docs says to just do the Reclast at 6 months and no need to rely on CTX). Another resource is Dr. Ben Leder's video on youtube entitled "Combinations and Sequencing."

Too early and too late with the Reclast are both possibly a problem. Do you have an endocrinologist and did they suggest a timing?

Since I had my last Prolia shot six months ago and was due for one on Feb. 17, she said now was a perfect time to make the switch since six months have passed. She said to time it correctly, we should do the new Reclast infusion in the middle of March so I'm scheduled for March 13th.

I had my first infusion of Reclast 3 weeks ago and feel absolutely fine. Not a great help to you, but it's something. I feel very positive about it.

That’s wonderful to hear! Thank goodness. I truly believe all these drugs are going to be an individual experience, both in results and side effects.
Wishing you continued success.

Was the Fosamax helping rebuild bone?

I will never have another Reclast infusion. I was so sick for almost 6 months. I am a year out and I still have a hard time sleeping. On another note has anyone heard that treatment for osteoporosis makes your bones denser but also more brittle???
I heard this from a physical therapist recently and shortly after that I caught myself from falling (tripped over something) and I have had so much pain since (about 2 weeks) that I am seeing a doctor next week. When I tripped and caught myself I had terrible pain in my thigh, hip, and back. It has not eased up -rather it has increased. Any info would be helpful. Thanks

Did you have a slow infusion with a lower dose or was it the "regular" amount? My understanding is that the bisphosphonates work by retarding the bone breakdown effects of the osteoclasts, which would normally remove old or damaged bone as opposed to medications like Tymlos that work with the osteoblasts to actually speed up the process of creating new bone. So, what this means in effect is that if your bone density is really low, and you have a high CTX score showing that you are breaking down much more bone than you're building, a bisphosphonate may be warranted to slow down the loss of bone. If the old bone isn't removed, this will increase your bone density but that bone may not be good quality bone. However, the catch is that IF you end up having to go on a bone builder medication later, it won't work as well as it would have if it was given first BEFORE the bisphosphonate. Insurance companies usually want you to "fail" on a bisphosphonate, meaning you can't handle the side effects, etc, before they will approve coverage for a bone builder medication. What all this means is that it is not an easy decision which medication to go on first, if any, and that you may have to fight your insurance company to cover the medication that you choose.

I was on Prolia for 3 yrs before I had my Reclast Infusion. I assume it was a regular does. Took about 45 minutes. I had horrible bone pain for 2 weeks over my entire body. I couldn't sleep-still can't. I had just about every side effect they listed and it lasted for 6 months.