Anyone take Anastrozole every other day?

Posted by kamra @kamra, Dec 5, 2024

I wonder if anyone here takes Anastrozole every other day. If so, does it lessen your side effects? Thank you.

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Profile picture for sharon35981 @sharon35981

@coco46 there is research that Exemestane taken Monday,, Wednesday , Friday is good enough. ❤️💕❤️

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@sharon35981 I have read a few different papers and articles about this, it's why I have decided to try it. Something I don't know though is if it's the same effectiveness for someone who has stage 4 BC spread into the bones. It's usually spoken about for someone who has had surgery/radiation/chemo type journey and is prescribed it for preventing recurrence.

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Profile picture for coco46 @coco46

@sharon35981 I have read a few different papers and articles about this, it's why I have decided to try it. Something I don't know though is if it's the same effectiveness for someone who has stage 4 BC spread into the bones. It's usually spoken about for someone who has had surgery/radiation/chemo type journey and is prescribed it for preventing recurrence.

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@coco46
Hello girlfriend ❤️ The research that mentions Exemestane taken three times a week is for Stage 0-2 BC. Wishing you the best. 💕❤️💕

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A couple of thoughts:
First, not knowing your complete cancer/medical picture I can't comment on your current medication regimen.
I will ask you about your experience/side effects with exemestane and verzenio since it looks like putting verzenio on board for me will take place. But not sure yet...will know more within a month or so.
Second, I do hear you loud and clear about not being a partner in your cancer treatment - about not being "heard" in your medical treatment or having a "say" on which direction YOU would like to take during your cancer journey.
And, yes, you are absolutely right - only YOU are on your personal health journey. No one else!
We are all individuals...all our cancer "stories", in which we all can relate to, are, however, different is so many ways.
Your story is not my story - yet we are ALL in the same boat. Just traveling individually on many different water-ways. We are all on the "cancer boat"...the boat no one wants to take a ride on. Ever. Yet, here we all are.
I feel for you coco46. You expressed gut-wrenching thoughts and feelings. I would strongly "suggest" you take back your life, in the manner in which YOU wish to live it. Regardless of how "uncomfortable" your medical provider is feeling - and, more importantly, how your medical provider is making YOU feel.
You are steering YOUR boat here. You are # 1 in your personal cancer story. You CAN make your own decisions here! Make YOUR cancer treatment plan according to what is in your mind, heart, body and soul.
What will make YOU comfortable in YOUR journey as you battle your illness? What is a "yes" and what is a "no"?
It is your choice. No matter what any physician might say - no matter what any physician tries to make you FEEL as you make these decisions. The stress and frustration you are feeling right now - described so eloquently in your posting now - is so very unhealthy for you. Stress is a killer in so many ways. Take your life back.
Make your life peaceful - according to YOUR terms. No one else's. You are so right. It's YOUR life.
And we all only get one go-around.
Do what it takes to take back YOUR control. YOUR state of health. Whatever it may be.
You deserve nothing less!
Blessings on your journey, be strong & find your peace.

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I've taken it every other day for the past year+ and have been on it since April 22, 2024. The side effects seem to be less, but they were ebbing after the first year of taking it every day, so I don't know if that's a correlation or a coincidence. I watched a video by Katie Couric who also has BC and she said that she'd experienced different side effects throughout her treatment regimen taking the same meds (not necessarily Anastrozole). I get that now. I am experiencing joint pain that I've never had, but I'm not certain if it's from the Anastrozole or the fact that I'm 75 and have been very active my entire life. Who knows? I only know I'm in this for the long haul and do as much as I can every single day.

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Profile picture for coco46 @coco46

@marshgirl24 @mir123 I wish I could, but I don't know where else to go. I can't drive myself anymore and the only people who drive me around, don't like driving very far. There are no good cancer centers near me, the only other one has even worse ratings and some worse doctors. I know people who went there and they said it was like a cattle drive... which is kind of how this place I go is starting to feel. The sad thing is that this place had great reviews when I started going there and now it's fallen down to 3 stars. I think they are taking on too many patients.
I got lucky and saw the nurse practitioner the last time and she was better than the doctor. I might be able to try and request that I see her more instead but I think she might work with another doctor normally. At least she listened to me and finally wrote down in my charts that I am not tolerating treatment well. I couldn't stand reading the lies in my chart anymore, it always says I am tolerating treatment great and have no complaints or side effects. After I had spent the whole appointment telling my doctor how terrible I feel and how I can't stand going on like this. I am always saying that same things about stress, everyone says to avoid and I feel like between the insurance company and the doctors, they have added huge amounts of unnecessary stress to my life.

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@coco46 Your situation sounds so difficult, and certainly can be overwhelming. I'm going to list a bunch of resources that might be helpful. although probably not all of them will work. It seems like talking to someone who can see the whole picture and can maybe advise you would be a help.
Nurse navigator for treatment in oncology.
Chaplain through hospital--can be non-denominational.
Oncology social worker, who can also help with transportation.
Palliative care.
Can your PCP help? Or refer?
Regular chaplain or counselor in community, if these appeal to you.
I find it difficult to make all these kinds of decisions alone, particularly if family is not a useful support. Is there anyone else you might trust to help you figure out exactly what you want and how get it? Wishing you all the best.

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Profile picture for Miriam, Volunteer Mentor @mir123

@coco46 Your situation sounds so difficult, and certainly can be overwhelming. I'm going to list a bunch of resources that might be helpful. although probably not all of them will work. It seems like talking to someone who can see the whole picture and can maybe advise you would be a help.
Nurse navigator for treatment in oncology.
Chaplain through hospital--can be non-denominational.
Oncology social worker, who can also help with transportation.
Palliative care.
Can your PCP help? Or refer?
Regular chaplain or counselor in community, if these appeal to you.
I find it difficult to make all these kinds of decisions alone, particularly if family is not a useful support. Is there anyone else you might trust to help you figure out exactly what you want and how get it? Wishing you all the best.

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@mir123 Thank you so much for the info, I don't know who or if any of those types of people are available in my area but I will see if I can find out. I am honestly surprised they never mentioned anything about palliative care yet at the cancer center I go to. Unless they don't offer that until someone is considered actively dying, like a hospice x amount of months given. I think all cancer centers should have palliative care involved from the very start, no matter your stage at diagnosis. I used to have a nurse navigator through the hospital when I was diagnosed but she cut ties after I was getting treatment through an unaffiliated cancer center.

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Profile picture for briarrose @briarrose

A couple of thoughts:
First, not knowing your complete cancer/medical picture I can't comment on your current medication regimen.
I will ask you about your experience/side effects with exemestane and verzenio since it looks like putting verzenio on board for me will take place. But not sure yet...will know more within a month or so.
Second, I do hear you loud and clear about not being a partner in your cancer treatment - about not being "heard" in your medical treatment or having a "say" on which direction YOU would like to take during your cancer journey.
And, yes, you are absolutely right - only YOU are on your personal health journey. No one else!
We are all individuals...all our cancer "stories", in which we all can relate to, are, however, different is so many ways.
Your story is not my story - yet we are ALL in the same boat. Just traveling individually on many different water-ways. We are all on the "cancer boat"...the boat no one wants to take a ride on. Ever. Yet, here we all are.
I feel for you coco46. You expressed gut-wrenching thoughts and feelings. I would strongly "suggest" you take back your life, in the manner in which YOU wish to live it. Regardless of how "uncomfortable" your medical provider is feeling - and, more importantly, how your medical provider is making YOU feel.
You are steering YOUR boat here. You are # 1 in your personal cancer story. You CAN make your own decisions here! Make YOUR cancer treatment plan according to what is in your mind, heart, body and soul.
What will make YOU comfortable in YOUR journey as you battle your illness? What is a "yes" and what is a "no"?
It is your choice. No matter what any physician might say - no matter what any physician tries to make you FEEL as you make these decisions. The stress and frustration you are feeling right now - described so eloquently in your posting now - is so very unhealthy for you. Stress is a killer in so many ways. Take your life back.
Make your life peaceful - according to YOUR terms. No one else's. You are so right. It's YOUR life.
And we all only get one go-around.
Do what it takes to take back YOUR control. YOUR state of health. Whatever it may be.
You deserve nothing less!
Blessings on your journey, be strong & find your peace.

Jump to this post

@briarrose Oh man I lost a really long post I had typed up in reply to you. I tried three times to post it and it wouldn't go through and when I refreshed again it was gone. I don't have the will right now to retype it but I do want to thank you right away for your reply. Your words of encouragement mean a lot.

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Profile picture for coco46 @coco46

@mir123 Thank you so much for the info, I don't know who or if any of those types of people are available in my area but I will see if I can find out. I am honestly surprised they never mentioned anything about palliative care yet at the cancer center I go to. Unless they don't offer that until someone is considered actively dying, like a hospice x amount of months given. I think all cancer centers should have palliative care involved from the very start, no matter your stage at diagnosis. I used to have a nurse navigator through the hospital when I was diagnosed but she cut ties after I was getting treatment through an unaffiliated cancer center.

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@coco46 Palliative care should just be an add-on as needed, not like hospice. I hope you can get it, as can be supportive.

REPLY
Profile picture for coco46 @coco46

@marshgirl24 @mir123 I wish I could, but I don't know where else to go. I can't drive myself anymore and the only people who drive me around, don't like driving very far. There are no good cancer centers near me, the only other one has even worse ratings and some worse doctors. I know people who went there and they said it was like a cattle drive... which is kind of how this place I go is starting to feel. The sad thing is that this place had great reviews when I started going there and now it's fallen down to 3 stars. I think they are taking on too many patients.
I got lucky and saw the nurse practitioner the last time and she was better than the doctor. I might be able to try and request that I see her more instead but I think she might work with another doctor normally. At least she listened to me and finally wrote down in my charts that I am not tolerating treatment well. I couldn't stand reading the lies in my chart anymore, it always says I am tolerating treatment great and have no complaints or side effects. After I had spent the whole appointment telling my doctor how terrible I feel and how I can't stand going on like this. I am always saying that same things about stress, everyone says to avoid and I feel like between the insurance company and the doctors, they have added huge amounts of unnecessary stress to my life.

Jump to this post

@coco46 That's exactly how I felt. The nurse practitioner I was seeing and who was much better for me than the oncologist is no longer at the cancer center, so today I got a new oncologist! What a breath of fresh air! Listened to me and was very encouraging! This was the first visit today and I can already tell this is going to be so much better for me!

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Regarding efficacy of taking aromatase inhibitor MWF vs daily.
1. The study of exemestane taken MWF instead of daily shows lowered estrogen levels--which is good. But it did not look at whether risk of recurrence was lowered. The risk might have been lowered similarly to higher dose--but that wasn't studied.
2. These results are similar to studies of other AIs taken MWF. Alternate day dosing works, in the sense that estrogen levels are lowered. But recurrence wasn't studied.
3. IMHO lower AI dosage and recurrence should be studied!
4. Blame big Pharma if you wish, but IMHO you're taking a risk not to take AI daily.

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