Anyone have a positive Cologuard test?

The 2 polyps removed were precancerous.

I had a false positive cologuard. My first, at 55, was negative. The second, at 58, was positive. That result I received via email. There was some small print that basically said 4% of positive cologuard results = CRC. The rest (51%) are either polyps (benign or pre-cancerous) or "no colorectal neoplasia" (45%). My colonoscopy found nothing at all. From the positive result to the procedure was exactly one month.

Welcome @gmaha67. I'm with @jakedduck1 about not leaping to the worst-case scenario. The fact that the Cologuard came back positive can be see as a good thing. Let me explain.

Colorectal cancer grows VERY slowly. It is unlikely that you have developed an advanced stage of cancer in the time between your two Cologuard tests. It is possible that the test picked up on your having benign or possibly pre-cancerous polyps.

As I wrote to @msrhray, getting a positive result from your Cologuard test is worrisome. But try to not worry until further investigations are done. It is possible that the Cologuard result is a false-positive, meaning there is no pre-cancer or cancer present. It may only signify that you have a benign polyp or pre-cancerous polyp. Colon cancer can be stopped in its tracks. It's good that you took the first step for detection.

Polyps are very common. I have had 2 colonoscopies and each time they removed both a benign and a pre-cancerous polyp. I have a colonscopy every 3 years and have never had cancer.

Do you have any questions about preparing for your colonoscopy?

I had a positive test but was from diverticulosis and a few polyps.
No big deal.
Don't think the worst.
Stay positive!!!
Good luck,
Jake

Hello. I had a positive cologuard come back positive. Having colonoscopy done this Monday. A little worried. My last cologuard was negative 3 years ago.

Had a cologuard come back negative at age 52. Now at age 55 had a positive Cologuard guard. 😟 Worried that a cancer has developed in that time.

My mom had a positive cologuard test and has had polyps removed. Please try not to worry and wait till they test the poly. Must polys are benign. I had a few benign polyps removed during my colonoscopy. Actually I truly do not worry about them because they are sissy’s benign. It’s good for the doctor to remove them because they may become cancerous in time. Good luck and let us know how you are
Sincerely Susan

I also had a positive Cologuard and just had my first colonoscopy yesterday at the age of 52. The doctor told me that there is a medium sized polyp at the base of my appendix that couldn't be removed safely due to risk of perforation and the fact that they cannot be sure that the polyp doesn't extend into the appendix. So I now I am waiting to hear the result of the biopsy. The doctor said that the polyp needs to be removed even if its just benign or precancerous (which I thought was the same thing) either by a highly skilled gastro surgeon or via an appendectomy. He said he'd be surprised if its cancerous but that would be a different conversation. I'm so confused and upset by all this.

Hi Colleen, I have Reflux/IBS for years treated with 2 daily medication twice daily. The colorgard box did mention not suitable for IBS patients, I think. I am still learning and am trying not to worry.
Thank you for your kind reply

@msrhray, welcome. I know that getting a positive result from your Cologuard test is hard. You're probably worried. But try to not worry until further investigations are done. It is possible that the Cologuard result is a false-positive, meaning there is no pre-cancer or cancer present. It may only signify that you have a benign polyp or pre-cancerous polyp. Colon cancer can be stopped in its tracks. It's good that you took the first step for detection.

I know the 16th seems far away, but it's only a few more days. How are you doing today?