Anyone else on Nucala for EGPA having sinusitis issues?
I have been on Nucala for EGPA for 15 months with good results while still on prednisone. I tapered slowly over 9 months and successfully stopped taking prednisone by August. By October my sinuses started acting up, exhibiting as inflammation of my sinuses, loss of sense of smell, difficulty sleeping due to blocked nose, inability to clear either by blowing my nose or post nasally. I have tried saline rinsing, Allegra, Xclear nasal spray, all to minor improvement. Halls sugar free cough drops will sometimes lessen the inflammation enough for broken sleep. I tried budesonide nasal spray which helps along with cough drop which helps me get some sleep.
I tried a short taper of prednisone back in January which solved all issues, only to have them return when I stopped. Wondering if this is a side effect of Nucala or a break through of EGPA? The notes on Nucala mention “ noisy breathing” and way down in lists “ unknown issues with congestion”.
Better than having the full blown disease, but wondering if anyone else has noticed this?
MTH13 still grateful.
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