Anyone else have EXTREME brain fog with dasatinib/imatinib?
My husband was just diagnosed in December with CML. He has also had Polycythemia Vera for 25 years, managed well with medication, most recently Jakafi until this CML diagnosis.
He was started on Dasatinib 100 mg, but he reacted with more than brain fog, more like dementia-level reaction. From making wiring diagrams to "what do I do with this medicine pack"? Dr took him off for a week, and the veil lifted. Switched him to Imatinib 400 mg, but we are seeing the same reaction.
It is a known but rare reaction to the TKIs, and we're meeting with his hem/onc again tomorrow to work on it. I'm wondering if anyone else has battled this. My dear engineer husband thought the initial itching was awful until this happened.
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