Anybody out there have medication induced Osteoporosis?

Posted by osteocurious @osteocurious, Feb 8 11:51am

I do. 45 years on antiseizure meds. 60 years old and feeling it. I feel like I lost time. New diagnosis and know prevention AND sustaining bone density is of utmost importance. My question - if you take a med that actively reduces the body’s ability to absorb calcium - what then? Do the OP meds help with absorption or just bone turnover and building? My concern is I will always be fighting the lack of absorption. Vit D facilitates this “normally” but I am not normal (😊) Nothing I have read talks about how to help with Calcium absorption of a med is blocking it. Any help is appreciated. Insee my doc again in March.

Interested in more discussions like this? Go to the Osteoporosis & Bone Health Support Group.

I banged my leg into a metal child/dog gate when I was walking in the dark in the middle of the night. Then I went right back to bed. (I should have iced and walked more) A clot traveled to my lungs but was misdiagnosed as pneumonia. That was around 15 years ago and most of that time I was on a very high dose of warfarin (15 mg. per day). Except for one anesthesiologist who spoke to me before a knee replacement I had no knowledge that was an extremely high dose. After 2 recent vertebra fractures I learned Warfarin probably did a number on my bones--I now have severe osteoporosis. I am on the blood thinner Eloquis for about the last year or so--and doing BHRT and strontium citrate (along with the other recommended supplements) in the hope my bones will benefit. I am very fearful of the bone drugs. I am 83.

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Profile picture for marjoram2 @marjoram2

I banged my leg into a metal child/dog gate when I was walking in the dark in the middle of the night. Then I went right back to bed. (I should have iced and walked more) A clot traveled to my lungs but was misdiagnosed as pneumonia. That was around 15 years ago and most of that time I was on a very high dose of warfarin (15 mg. per day). Except for one anesthesiologist who spoke to me before a knee replacement I had no knowledge that was an extremely high dose. After 2 recent vertebra fractures I learned Warfarin probably did a number on my bones--I now have severe osteoporosis. I am on the blood thinner Eloquis for about the last year or so--and doing BHRT and strontium citrate (along with the other recommended supplements) in the hope my bones will benefit. I am very fearful of the bone drugs. I am 83.

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@marjoram2
I am so sorry for your struggles. You have been through significant challenges. I am new to osteoporosis - perhaps someone else here can offer you hope and guidance based on their experience.
We are learning from the responses to my question that we receive no heads up from providers about the potential bone density loss from different common meds. There must be something we can do to advocate for providers to be more responsible for informing us.
I notice here there are many others with trepidation about the meds, including me.
Please take care and reach out with your questions. ❤️

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Profile picture for nycmusic @nycmusic

I have heard that levothyroxine can affect bones…if so, when docs prescribe it,maybe they should recommend things we can do to keep bones strong—exercises, diet, supplements…

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@nycmusic I completely agree. We are not properly informed that a life changing physical side effect is a possibility. I gander that the providers are not even aware.
When I showed my primary care provider my supplements she said they wouldn't help. Huge red flag.
My mom was on multiple meds that we now know affect bone density and she was also on levothyroxine. For years. I wonder if that also contributed to her fractures? Boy. We should start a database!

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Profile picture for osteocurious @osteocurious

@nycmusic I completely agree. We are not properly informed that a life changing physical side effect is a possibility. I gander that the providers are not even aware.
When I showed my primary care provider my supplements she said they wouldn't help. Huge red flag.
My mom was on multiple meds that we now know affect bone density and she was also on levothyroxine. For years. I wonder if that also contributed to her fractures? Boy. We should start a database!

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@osteocurious yes, a database—is there one anywhere else ? If not, begin here !

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Profile picture for nycmusic @nycmusic

I have heard that levothyroxine can affect bones…if so, when docs prescribe it,maybe they should recommend things we can do to keep bones strong—exercises, diet, supplements…

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@nycmusic
Most of the concern was with higher TSH levels.
But....
There is at least one study of around 450 people with 81 euthyroid levothyroxine users done at John Hopkins.
The conclusion was this: “Our study suggests that even when following current guidelines, levothyroxine use appears to be associated with greater bone loss in older adults,” said Shadpour Demehri, M.D., co-senior author and professor of radiology at Johns Hopkins.
It seems there was more concern in older adults. (what else is new, ha)
https://www.rsna.org/media/press/i/2538
Interestingly, this study seems to be even more nuanced in that this research had a particular profile: 70 and older, T4 only no T3, normal tsh but free t4 was often high, normal free t3 was low normal, already declining bone density, taking no BHRT or HRT, no strontium therapy.
This profile was extracted by copilot from numerous different sources. If you want a list just put the question into copilot, and it will list them for you.

Whatever the situation it seems conservative for those of us on thyroid hormone to watch our bone health carefully and to observe best practices.

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Profile picture for nycmusic @nycmusic

@osteocurious yes, a database—is there one anywhere else ? If not, begin here !

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@nycmusic
What a great link thank you.
I have shared the link on Inspire; I will gladly say that you provided the information if you don't mind your name being placed on this post:
https://www.inspire.com/m/Kathleen1314/journal/eb5c44-a-comprehensive-list-of-medicines-that-cause-bone-loss/

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Profile picture for mcchesney @kathleen1314

@nycmusic
What a great link thank you.
I have shared the link on Inspire; I will gladly say that you provided the information if you don't mind your name being placed on this post:
https://www.inspire.com/m/Kathleen1314/journal/eb5c44-a-comprehensive-list-of-medicines-that-cause-bone-loss/

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@kathleen1314
Not a problem. I found it like anybody else can. 🙂

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@osteocurious thanks…nbihealth is interesting….i also read the alkaline/acidic info..good to be aware of, but it’s all about balance in the end…

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Profile picture for mcchesney @kathleen1314

@nycmusic
Most of the concern was with higher TSH levels.
But....
There is at least one study of around 450 people with 81 euthyroid levothyroxine users done at John Hopkins.
The conclusion was this: “Our study suggests that even when following current guidelines, levothyroxine use appears to be associated with greater bone loss in older adults,” said Shadpour Demehri, M.D., co-senior author and professor of radiology at Johns Hopkins.
It seems there was more concern in older adults. (what else is new, ha)
https://www.rsna.org/media/press/i/2538
Interestingly, this study seems to be even more nuanced in that this research had a particular profile: 70 and older, T4 only no T3, normal tsh but free t4 was often high, normal free t3 was low normal, already declining bone density, taking no BHRT or HRT, no strontium therapy.
This profile was extracted by copilot from numerous different sources. If you want a list just put the question into copilot, and it will list them for you.

Whatever the situation it seems conservative for those of us on thyroid hormone to watch our bone health carefully and to observe best practices.

Jump to this post

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