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Anybody Get FOLFOX Chemo After Metastatic Diagnosis?
After surgery to partially remove my colon 18 months ago, the PETscan this month found a small growth on the outer lining of my liver. Pathology said it's likely Stage II metastatic tumor. Oncology asks whether I would accept chemotherapy treatment and suggested use of the FOLFOX chemo on it. I have to decide the broader chemo question AND the specific FOLFOX issue. Any advice on the choice and the experience would be deeply appreciated. Martin
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Im having the same thing unfortunately My doc is starting me on oral Xeloda 14 days on 7 days off then a few rounds of Oxaliplatin. I also checked with City of Hope and they do the same regimen. After treatment if there are any signs of the tumor still on liver they will go in to to an ablashia on the liver I feel comfortable doing it especially confirming my oncologist and my colon oncologist stated this along with City of Hope and the second opinion of the same treatment Let me know how you proceed and prayers for all of us F cancer and lets beat this together
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1 ReactionI am currently in the middle of FOLFOX 6 treatment. I have Stage 4 rectal cancer that metastasized to a lymph node and a small spot in the lung. So far side effects have been manageable. I have been experiencing nausea, diarrhea, and some neuropathy, but am doing acupuncture and PT to help. The weirdest side effect for me has been the cold sensitivity due to the oxaliplatin. My midway CT scan did not show any nodule in the lung, which seems to indicate treatment is working.
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1 Reaction@madilworth - I'm really glad to hear your midway CT scan showed no nodule in the lung—that’s incredibly encouraging and suggests the FOLFOX 6 treatment is having a positive impact! The cold sensitivity from oxaliplatin is definitely a strange and common side effect; it can feel like a shock to the system when touching cold surfaces or drinking cold liquids. It sounds like you’re managing the nausea, diarrhea, and neuropathy well with acupuncture and physical therapy—great job staying proactive. Since you’re handling things but might want some additional tips, here are a few practical ideas for dealing with cold sensitivity and other side effects, along with some general guidance:
Cold Sensitivity (Oxaliplatin-Induced): This happens because oxaliplatin can cause temporary nerve irritation, leading to tingling or discomfort with cold exposure. To help:
Wear gloves when reaching into the fridge or freezer, and keep warm socks or slippers handy for cold floors.
Use room-temperature or warm drinks and foods to avoid throat or mouth sensitivity. A scarf or face covering can help if you’re outside in chilly weather.
Some patients find relief by keeping a warm blanket or heating pad nearby for comfort during infusions or at home.
Since this is a neuropathy-related effect, let your oncologist know if it worsens or persists, as they might adjust the dose or schedule to reduce nerve impact. This might seem counterintuitive but the next time you are having your oxalaplatin infusion, try wrapping your fingers in a cold pack. The chemo nurses typically keep these on hand. What you are doing is limiting the amount of drug into the fingertips and preventing the drug from affecting the nerves. Could you give that a try and let me know if it works?