Antacid abuse? When is it too much?

Posted by raykemble @ray666, Jan 4 9:53am

I'm embarrassed to say that I've been an OTC antacid abuser (Tums, etc.), often eating them like candy. Now I'm wondering if my various gastrointestinal discomforts might have been caused by the abuse. Does this sound familiar to anyone?

Interested in more discussions like this? Go to the Digestive Health group.

Hello Ray @ray666, I think that is a good question. I've never used them much but I did find a few references on the topic that may help some until other members with some experience can respond.

"Serious side effects can occur with an overdose or overuse of antacids. Side effects include constipation, diarrhea, change in the color of bowel movements, and stomach cramps. Products containing calcium may cause kidney stones and are more likely to cause constipation." — Frequently Asked Questions About Heartburn and Reflux: https://www.webmd.com/heartburn-gerd/heartburn-faq

"Antacid ingestion may lead to side-effects related to their chemical … function is unlikely unless there is an abuse of these "over the counter" antacids." — Antacid therapy–changes in mineral metabolism: https://pubmed.ncbi.nlm.nih.gov/6293043/

"Antacid abuse: a rare cause of severe hypercalcaemia … it was found that this patient had troublesome dyspepsia symptoms for which he had …" — Antacid abuse: a rare cause of severe hypercalcaemia – NCBI: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5747649/

Have you had a chance to discuss the symptoms with your doctor?

REPLY
@johnbishop

Hello Ray @ray666, I think that is a good question. I've never used them much but I did find a few references on the topic that may help some until other members with some experience can respond.

"Serious side effects can occur with an overdose or overuse of antacids. Side effects include constipation, diarrhea, change in the color of bowel movements, and stomach cramps. Products containing calcium may cause kidney stones and are more likely to cause constipation." — Frequently Asked Questions About Heartburn and Reflux: https://www.webmd.com/heartburn-gerd/heartburn-faq

"Antacid ingestion may lead to side-effects related to their chemical … function is unlikely unless there is an abuse of these "over the counter" antacids." — Antacid therapy–changes in mineral metabolism: https://pubmed.ncbi.nlm.nih.gov/6293043/

"Antacid abuse: a rare cause of severe hypercalcaemia … it was found that this patient had troublesome dyspepsia symptoms for which he had …" — Antacid abuse: a rare cause of severe hypercalcaemia – NCBI: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5747649/

Have you had a chance to discuss the symptoms with your doctor?

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Hi, John (@johnbishop)

Thanks for those links! Quoting from the first link––"Side effects include constipation, diarrhea, change in the color of bowel movements, and stomach cramps"––my symptoms precisely! I've not discussed this lately with my primary, but she and I have talked about my gastro woes at earlier visits. I was referred to a gastroenterologist, who was dismayed to learn how many OTC medications I'd been using all in an attempt to bring peace and harmony to my gut. The gastroenterologist advised I take a magnesium supplement and NOTHING else––and in time I began to feel great. Of course, that was a few years ago. In the ensuing years, I fell back on my old bad habits: a daily smorgasbord of Metamucil, Tums, Miralax … you name it, I probably took it. As of today, other than the daily magnesium, I'm done with all that other stuff. Again, John, thanks for your message. I've got a lot to learn!

Ray (@ray666)

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@ray666

Hi, John (@johnbishop)

Thanks for those links! Quoting from the first link––"Side effects include constipation, diarrhea, change in the color of bowel movements, and stomach cramps"––my symptoms precisely! I've not discussed this lately with my primary, but she and I have talked about my gastro woes at earlier visits. I was referred to a gastroenterologist, who was dismayed to learn how many OTC medications I'd been using all in an attempt to bring peace and harmony to my gut. The gastroenterologist advised I take a magnesium supplement and NOTHING else––and in time I began to feel great. Of course, that was a few years ago. In the ensuing years, I fell back on my old bad habits: a daily smorgasbord of Metamucil, Tums, Miralax … you name it, I probably took it. As of today, other than the daily magnesium, I'm done with all that other stuff. Again, John, thanks for your message. I've got a lot to learn!

Ray (@ray666)

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Hoping you can find some answers soon!

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@johnbishop

Hoping you can find some answers soon!

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Find answers Me too! I'll keep watching this forum, If others should chime in to say they, too, have been or are abusing OTC gastrointestinal problems, I'll keep them posted on my progress. I'm thinking of what I'm doing as a kind of detox. ––Ray

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@ray666

Find answers Me too! I'll keep watching this forum, If others should chime in to say they, too, have been or are abusing OTC gastrointestinal problems, I'll keep them posted on my progress. I'm thinking of what I'm doing as a kind of detox. ––Ray

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Whoops! I meant to say: " … to say they, too, have been or are abusing OTC gastrointestinal MEDICATIONS … "

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@ray666

Hi, John (@johnbishop)

Thanks for those links! Quoting from the first link––"Side effects include constipation, diarrhea, change in the color of bowel movements, and stomach cramps"––my symptoms precisely! I've not discussed this lately with my primary, but she and I have talked about my gastro woes at earlier visits. I was referred to a gastroenterologist, who was dismayed to learn how many OTC medications I'd been using all in an attempt to bring peace and harmony to my gut. The gastroenterologist advised I take a magnesium supplement and NOTHING else––and in time I began to feel great. Of course, that was a few years ago. In the ensuing years, I fell back on my old bad habits: a daily smorgasbord of Metamucil, Tums, Miralax … you name it, I probably took it. As of today, other than the daily magnesium, I'm done with all that other stuff. Again, John, thanks for your message. I've got a lot to learn!

Ray (@ray666)

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I feel better taking magnesium daily after the same kind of behavior others have described with antacids etc. I do take a pepcid occasionally. What about the magnesium and giving up the others works? I would like to know because I figured this out for myself by the way I feel. It helped with constipation and chronic nausea I had for years.

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@tarmansbks

I feel better taking magnesium daily after the same kind of behavior others have described with antacids etc. I do take a pepcid occasionally. What about the magnesium and giving up the others works? I would like to know because I figured this out for myself by the way I feel. It helped with constipation and chronic nausea I had for years.

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I found a great article explaining the benefits of magnesium for you.

My only previous exposure to magnesium was when I was child and my mom would ply me with Milk of Magnesia to keep ‘me going’ when I experienced constipation. Apparently that was the go-to med back in the day. Gack! I can still taste it and that’s more than 60+ years ago! 😅

However, during my bone marrow transplant one of the major factors I was checked for daily, was my magnesium level. It’s important in regulating so many functions in the body and one of my meds seriously depleted that amount daily. So initially, daily IV infusions of mag were given. As my meds changed, so did the dosage of Mag. Now I really don’t have to take it but I do because I’m finding it helps promote good sleep for me. I feel better, more energetic, my bone health is improving and my distestive tract is happy!
My husband now takes a daily dose as well. He also sleeps better and has seen other health symptoms, including his digestion have improved.
I take magnesium glycinate because it doesn’t cause any of the side effects for me such as gas or diarrhea that comes with magnesium citrate.

What magnesium suppliment do you take?
https://www.medicalnewstoday.com/articles/286839#recommended-daily-intake

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@loribmt

I found a great article explaining the benefits of magnesium for you.

My only previous exposure to magnesium was when I was child and my mom would ply me with Milk of Magnesia to keep ‘me going’ when I experienced constipation. Apparently that was the go-to med back in the day. Gack! I can still taste it and that’s more than 60+ years ago! 😅

However, during my bone marrow transplant one of the major factors I was checked for daily, was my magnesium level. It’s important in regulating so many functions in the body and one of my meds seriously depleted that amount daily. So initially, daily IV infusions of mag were given. As my meds changed, so did the dosage of Mag. Now I really don’t have to take it but I do because I’m finding it helps promote good sleep for me. I feel better, more energetic, my bone health is improving and my distestive tract is happy!
My husband now takes a daily dose as well. He also sleeps better and has seen other health symptoms, including his digestion have improved.
I take magnesium glycinate because it doesn’t cause any of the side effects for me such as gas or diarrhea that comes with magnesium citrate.

What magnesium suppliment do you take?
https://www.medicalnewstoday.com/articles/286839#recommended-daily-intake

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Thank you for this explanation. I take magnesium oxide and when the bottle is gone I had planned to get magnesium glycinate. I do sleep much better at night and even my recent sleep test didn't indicate anything too awful or worrisome. My digestive tract is much better. I have osteopenia and I hope it will help because the prolia shot made me very sick. My mother and sister lived to old age and never took a medication to promote bone health. My mother was a widow for 34 years and stayed in her two story home from 1945 until 2008 when she died. I am hoping to avoid any bone densifiers and consider it a victory over my gut and sleep issues that magnesium is so easy. M.E.

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@tarmansbks

Thank you for this explanation. I take magnesium oxide and when the bottle is gone I had planned to get magnesium glycinate. I do sleep much better at night and even my recent sleep test didn't indicate anything too awful or worrisome. My digestive tract is much better. I have osteopenia and I hope it will help because the prolia shot made me very sick. My mother and sister lived to old age and never took a medication to promote bone health. My mother was a widow for 34 years and stayed in her two story home from 1945 until 2008 when she died. I am hoping to avoid any bone densifiers and consider it a victory over my gut and sleep issues that magnesium is so easy. M.E.

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You’re most welcome. It’s great you’d feeling the benefits of the magnesium. Regarding bones, from my experience with bone loss from chemo/transplant I found the magnesium played a huge roll in building bone density.
I was dismayed to see my first Dexa scan post transplant. Before the crazy cancer journey my Dexa scan didn’t even indicate osteopenia! So I was wide-eyed in shock to see I had osteoporosis. My transplant doctor wanted to start on bisphosphonates to which I resisted. I wanted to try rectify things on my own.
So along with diet and supplements, I added weight bearing exercises which helped reverse the bone loss.

I found a previous conversation I posted a while back. Here’s the link to what has worked for me. Since I wrote that reply, I’ve had a 3rd Dexascan and I’m holding my own with slight osteopenia. I’ve upped my exercises by adding leg weights of 3 pounds.
https://connect.mayoclinic.org/comment/638453/
Have you tried any exercises specially for hip and spine?

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Good morning, tarmansbks (@tarmansbks) and Lori (@loribmt),

You can't imagine how cheered I was to find your posts! Yesterday, when I started this thread, I was truly embarrassed about having gone so hog-wild on all those OTC gastrointestinal drugs. This morning I feel less alone.

Lori, I smiled when I read how your mother would ply you with Milk of Magnesia! Mine did too. And naturally in the recent months, among my many (too many) OTC drugs, I've been taking Phillip's Milk of Magnesia, not every day, but whenever I'd feel it was time for a good, thorough cleansing.

I see in your posts that three different magnesium "formulations" are mentioned: magnesium glycinate, magnesium citrate, and magnesium oxide. I just checked: I've been taking magnesium oxide, 500 mg, one tab per day. Based upon your experiences, would you suggest I change to either glycinate or citrate?

I should probably mention that I too have arthritis. My two worst sore spots are my left knee (my right knee is already a replacement) and my left hip. I am seeing an orthopedic doctor for these. At the moment, she's not advising either a knee or hip replacement (or both); instead, I've been receiving injections (which help, if minimally). She also has me on Diclofenac Sodium, delayed tabs, 75 mg, twice daily. For the past few months, in addition, I have been going to PT for knee, hip, and spine (to boot, I have a "borderline" case of cervical myelopathy).

Again, let me say your posts make me feel less alone!

Ray (@ray666)

REPLY
@ray666

Good morning, tarmansbks (@tarmansbks) and Lori (@loribmt),

You can't imagine how cheered I was to find your posts! Yesterday, when I started this thread, I was truly embarrassed about having gone so hog-wild on all those OTC gastrointestinal drugs. This morning I feel less alone.

Lori, I smiled when I read how your mother would ply you with Milk of Magnesia! Mine did too. And naturally in the recent months, among my many (too many) OTC drugs, I've been taking Phillip's Milk of Magnesia, not every day, but whenever I'd feel it was time for a good, thorough cleansing.

I see in your posts that three different magnesium "formulations" are mentioned: magnesium glycinate, magnesium citrate, and magnesium oxide. I just checked: I've been taking magnesium oxide, 500 mg, one tab per day. Based upon your experiences, would you suggest I change to either glycinate or citrate?

I should probably mention that I too have arthritis. My two worst sore spots are my left knee (my right knee is already a replacement) and my left hip. I am seeing an orthopedic doctor for these. At the moment, she's not advising either a knee or hip replacement (or both); instead, I've been receiving injections (which help, if minimally). She also has me on Diclofenac Sodium, delayed tabs, 75 mg, twice daily. For the past few months, in addition, I have been going to PT for knee, hip, and spine (to boot, I have a "borderline" case of cervical myelopathy).

Again, let me say your posts make me feel less alone!

Ray (@ray666)

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Ray, as my mom used tell me, at a time when I was too young to appreciate her wisdom, “There’s nothing new under the sun!” And now that I’m at that ‘age of wisdom’ her words ring true all the time. There are very few issues we face that someone hasn’t walked that path before us.

Mayo Connect is a great source of community for members, isn’t it? We realize we’re not having to face all these uncertainties alone. It’s a comfortable place to virtually sit around the table with ‘family’ and hash things out! So I’m glad you’re here with us too!

Ok, Ray, I gotta say, back off the Milk of Magnesia! 😂 You willingly take that? No one has to be cleaned out that well. I’m not a doctor and can’t make any suggestions but as a mother and ‘a woman of age’, I can nudge you in the direction of backing off the antacids and tums if you don’t need them for heartburn. Even the peppermint in some of those antacids can irritate your digestive system.
But from experience with having to take a proton pump inhibitor (Protonix) you don’t want to drop that stuff cold Turkey either. You can have acid rebound from too much stomach acid when your own body starts taking over the control of acid production again.

As far as the different forms of Magnesium, the mag glycinate was found, for me, to be the least irritating to my sensitive guts. It was approved by my transplant team pharmacist after I researched what was kindest to the digestive tract. When I was switched from IV mag to pills. I had a bottle of Mag Citrate for the next step. Well, I took 1 tablet as prescribe. Oh lord…within 20 minutes flashbacks of my childhood with the M of Mag came back to haunt me!! Craziness ensued in my nether regions and I vowed never to take THAT again! So that’s how I ended up with the kinder, gentler form of Magnesium.

Can I ask, why did you start taking the OTC antacids in the first place? I think I may have missed that conversation.

REPLY
@ray666

Good morning, tarmansbks (@tarmansbks) and Lori (@loribmt),

You can't imagine how cheered I was to find your posts! Yesterday, when I started this thread, I was truly embarrassed about having gone so hog-wild on all those OTC gastrointestinal drugs. This morning I feel less alone.

Lori, I smiled when I read how your mother would ply you with Milk of Magnesia! Mine did too. And naturally in the recent months, among my many (too many) OTC drugs, I've been taking Phillip's Milk of Magnesia, not every day, but whenever I'd feel it was time for a good, thorough cleansing.

I see in your posts that three different magnesium "formulations" are mentioned: magnesium glycinate, magnesium citrate, and magnesium oxide. I just checked: I've been taking magnesium oxide, 500 mg, one tab per day. Based upon your experiences, would you suggest I change to either glycinate or citrate?

I should probably mention that I too have arthritis. My two worst sore spots are my left knee (my right knee is already a replacement) and my left hip. I am seeing an orthopedic doctor for these. At the moment, she's not advising either a knee or hip replacement (or both); instead, I've been receiving injections (which help, if minimally). She also has me on Diclofenac Sodium, delayed tabs, 75 mg, twice daily. For the past few months, in addition, I have been going to PT for knee, hip, and spine (to boot, I have a "borderline" case of cervical myelopathy).

Again, let me say your posts make me feel less alone!

Ray (@ray666)

Jump to this post

Ray, I found this for you!

Magnesium Citrate
Magnesium citrate is one of the most popular and easily absorbed magnesium supplements. In this form, magnesium is bound to citric acid (a large molecule), so there is a smaller amount of elemental magnesium per capsule. Because citric acid is a mild laxative, magnesium citrate is an excellent choice for individuals with occasional constipation.

Magnesium citrate is a laxative at high doses, which means it causes stool to retain water, making it softer. As a result, taking this supplement may lead to more bowel movements and makes it easier to pass stool.

Fortunately, you won’t need to change your diet when taking these supplements. Nevertheless, you’ll want to inform your doctor if you have any allergies, prescriptions, medications, or conditions that could affect the magnesium citrate.
~~~
Magnesium Oxide
Magnesium oxide is one of the least absorbed forms. Still, because the oxide molecule is small and compact, it delivers one of the highest percentages of elemental magnesium per dose, making it a practical choice for someone who wants to take as few capsules as possible.

Because it is not as quickly absorbed in the intestine, magnesium oxide has more osmotic (water-attracting) effects in the colon, providing support for those with occasional constipation.

Some people also take it as an antacid to help relieve issues like stomach acid, heartburn, or indigestion. Like magnesium citrate, magnesium oxide at high doses can also work as a laxative to facilitate bowel movements for those going into surgery.
~~~~~
Magnesium Glycinate
Magnesium glycinate is a gentle form for individuals who are sensitive to magnesium oxide or citrate, as it is less likely to cause a laxative effect. In this form, magnesium is bound to glycine, a non-essential amino acid involved in protein synthesis and transmission of chemical signals in the brain.

Glycine is considered a relaxing neurotransmitter and may enhance magnesium’s natural calming properties. This may be one of the best types for promoting relaxation and good quality sleep. So, if you struggle with mood and stress related challenges, you can take magnesium glycinate to help alleviate the symptoms.

In addition to promoting a positive mental state, this supplement is also great for promoting bone health, maintaining proper heart rhythm, maintaining healthy blood sugar levels, and reducing symptoms of premenstrual syndrome. Some people also use it to reduce pain and enhance physical performance during exercise.

Magnesium glycinate is a great option for people who don’t absorb magnesium well. Unfortunately, this mineral can still cause some stomach upset, which is why it’s recommended you take it with food. Also, you should take note of the amount of magnesium in the supplements you take for your safety.
~~~~
Magnesium Malate
Another gentler form of magnesium – for individuals who may be more sensitive to magnesium oxide or citrate – is magnesium malate. It is often recommended for people looking for energy support since malic acid – a natural fruit acid present in most cells in the body – plays a crucial role in ATP synthesis and energy production.

Magnesium malate is absorbed more readily compared to other magnesium supplements. Like other magnesium supplements, magnesium malate can produce a laxative effect, and can provide cranial nerve comfort support related to magnesium deficiency. Magnesium malate may also help to boost your mood.
https://ods.od.nih.gov/factsheets/Magnesium-Consumer/

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