Over two years out from initial Stage1 diagnosis. Lumpectomy followed by radiation, then began taking anastrozole for about 6-7 months. Side effects, mostly bone pain that eventually moved to my feet, were horrible as my job requires a lot of walking. Doc recommended a stay in the meds for about two weeks. Felt like a new person! I’m currently on Letrozole which has been a better fit for me until the last few months. Hair thinning (also happened with anastrozole); HOT FLASHES, severe fatigue, bone pain mainly in my hips, and depression. Not sleeping well, but Dr. isn’t sure that’s Letrozole. He gave me the option of coming off Letrozole for 7-10 days to see if I noticed a difference. If I improve, I’ll next try Tamoxifen. I know everyone reacts diffently to these meds, but I’d certainly appreciate some feedback from you guys before I make another change. Thanks so much!