Anastrazole and anxiety

Posted by momandrph048 @momandrph048, Jun 14, 2023

Has anyone else taking an aromatase inhibitor been dealing with crying very easily, and anxiety that comes out of nowhere?? It doesn’t seem to be related to anything, it just appears out of the blue.. My oncologist has me on Effexor, but it doesn’t seem to be doing that much and I really don’t want to increase my dose.. Can anyone share a similar story? Counseling isn’t really for me, I just need to deal with it on my own, and I really feel that the medication is the reason for it.. Mostly because my dr had me stop it for a couple weeks due to joint pain and everything got better.. Thanks for your input!

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It could be causing the crying. Its blocking the estrogen. When you were younger, your body made estrogen. Did you cry then?
The offset to get balance is progesterone.p or progesterone cream. However, if your cancer feeds on progesterone, you may not be able to use it. Your onc can tell you if your cancer fed off progesterone and what percentage.
The crying could be a part of PSTD. The trauma you went thru with dealing with the cancer might be post traumatic stress. Too consumed with treatment, surgery & radiatio hen once its over youre left alone.
Get your hormones checked and see how progesterone effects your cancer.
If progesterone doesn't feed your cancer, talk to a doctor about yam cream or progesterone cream. Better yet, read Dr JohnLees Book on Breast cancer and
Estrogen dominance. He believed osteoporosis could be revered by the cream and observed this to be true with many, many of his patients.

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@cberge67

Thank you all for sharing your journey.
Today is day one of taking Anastrozole and your experience has been very helpful. I’m trying not to overthink the situation but it is a challenge to keep looking forward.
Im trying to figure out what time of day will work best.
Thanks again!

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I have been taking anastrozole for almost 2 years I take mine at night right after dinner. It helps with hot flashes and headache I sleep through it.
Hope this helps.

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Thank you all for sharing your journey.
Today is day one of taking Anastrozole and your experience has been very helpful. I’m trying not to overthink the situation but it is a challenge to keep looking forward.
Im trying to figure out what time of day will work best.
Thanks again!

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I'm taking exemestane after one year with anastrozole (due to fingerstiffness). Still having joint pain but manageable. I'm taking turmeric, vit D, glucosamine, and occasionally magnesium glycinate.

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@momandrph048

Just be careful about turmeric if you take an aromatase inhibitor , ask your oncologist because I think they can decrease the effect of anastrazole..

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I told my oncologist about taking turmeric. She said it's ok. Turmeric reduces inflammation.

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I was diagnosed with Stage 1a-b breast cancer in 2020. I had a lumpectomy, a second surgery to clear the margins, 16 rounds of radiation and then started to take anastrozole which was the most difficult part of my treatment. The side effects, which were from head to toe, resulted in a very poor quality of life. I can definitely relate to your anxiety. I was severely depressed. My oncologist, at the time, did not acknowledge any of my symptoms as being caused by anastrozole. Sadly, this seems to be a common complaint on this forum. At the only appointment my husband was able to attend because of covid, he told the doctor that the medicine had changed my whole personality. I was aware that I had not been myself, but his comment summed it up for me. He was always more than patient with me but was trying to impress upon the doctor that the medicine was indeed having an extremely negative effect on me. I decided to stop taking the medicine after about 2 1/2 months. The side effects subsided. I also started walking which I have continued to do every day for over 3 years.
I know that I am fortunate that my Stage 1 cancer was discovered early, and my chances of recurrence are lower than many others. I would never suggest that anyone not try to take an aromatase inhibitor. These medicines affectCs everyone differently and you can always stop. We each have to make decisions based on many factors - stage of cancer, age, other health issues, family situation, etc. However, it is our decision to make. There will always be a part of me that wonders if I made the right decision.
I hope this input is helpful. I wish you all best of luck in your treatment and good health in the years to come.

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@flowergal

Thank you. I am using Tumeric and tart cherry to help ( found here I believe).

Luckily I sleep well. I agree my body has been through a lot. We all have.

Yes one day at a time. 🙂

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Just be careful about turmeric if you take an aromatase inhibitor , ask your oncologist because I think they can decrease the effect of anastrazole..

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Thank you for sharing. I know that admitting emotional "out of controlness" is scary . I have been on Letrozole for 4 months and have spontaneous anxiety attacks and strong mood swings, sometimes, seemingly unrelated to anything at all. I have talked with my loved ones- apologizing in advance for my spontaneous swings. I practice care and grounding through yoga, other forms of exercise, art therapy, meditation- the list goes on. It doesn't stop them from happening but dulls my responsiveness to it. And I remind myself that the chemical changes in my body are not "me"- they are just that- chemical responses. I feel you sister.

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@mpirruccel

I think this whole experience of having had breast cancer is so traumatic that fatigue is one part of processing the journey. Try taking some short walks as that might get the blood flowing and give you a bit of energy. The estrogen blockers can also cause insomnia so if you’re not sleeping well at night daytime fatigue happens. I use turmeric to help with the joint pain although I already had arthritis. One day at a time!

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Thank you. I am using Tumeric and tart cherry to help ( found here I believe).

Luckily I sleep well. I agree my body has been through a lot. We all have.

Yes one day at a time. 🙂

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@gegost1955

I would try a different time when you take the medicine.
I take Anastrozole now for 1 1/2 years and deal with muscle pain fatigue and tiredness. I got extremely tired 8 hours after I took it - the time I had to drive home. Literally to the point where I could not keep my eyes open. I am taking it now 7-8 hours BEFORE I want to go to sleep and that made a great difference. I also walk every day in the afternoon - that helps with the muscle pain.

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I am taking it at 5 pm. Trying to get the major hot flashes out of the way. They can drench whatever I'm wearing.

Not sure what other time I could try. By 1:30 I have to nap.
I guess it could be related to something else too.

Most things that require energy I have to do in the mornings
( like the gym).

Thanks for your reply.

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