Aromatase Inhibitors: How to choose and manage side effects?

Posted by shebell @shebell, Sep 11, 2024

I was diagnosed in April 2024 stage 1 invasive ductal carcinoma - estrogen positive. I had lumpectomy and radiation my onco score was 12 so was able to skip chemo therapy. I have tried Anastrozole and had terrible side effects I have not tried Tamoxifen yet and am seriously thinking about forgoing any AI long term treatment has anyone else made that choice?

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@flatland

So many here have mentioned that the AIs reduce the recurrence rate by 50%. I have been told that as well, but isn't that just a general statement? I don’t know exactly how to say this in mathematical terms, but your personal type of cancer, lymph node involvement, etc all come into play and ultimately lower that number.

I’m saying this because so many on this site have a better understanding than I have, and can help me figure out- or better weigh my options with these drugs.

I had two tumors in my right breast, stage one and stage 2 triple positive ductal carcinoma. So chemo, lumpectomy, radiation and now 5 years of AIs. I am currently cancer free, and I’ve had some issues with the medication. I don’t really want to take it. I took anastrzole first, had some leg pain and switched to extremestan gained weight, and now back to anastrazole. After going through all this I don’t want to essentially waste those efforts by not completing the treatment, but if the recurrence rate is a much lower number I’d rather be comfortable at 73.

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Now the doctors are telling you to stay on it 10 years, meaning forever

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