ANDROGEN DEPRIVATION.THERAPHY FOR SHORT OR LONG TERM?

Posted by zonanaa @zonanaa, 8 hours ago

I am 66 yrs old, highest PSA before prostatectomy wss 9 ng_mL.
I had radical prostatectomy, Gleason score of 4+3 and posiive surgery margins with Gleason 3. PET scan m1T2m miNo miMo
Post-surgery PSA of 0.48 ng/mL
Actually salvage radiotherapy 20 of 35 sessions and ADT, Goserelin, first trimestral dosis.
My concetn is the use of ADT short-term (4-6 months) or long-term (24 months) ? Thank you for comnents
Abraham

Interested in more discussions like this? Go to the Prostate Cancer Support Group.

surftohealth88 | @surftohealth88 | 8 hours ago

This is what the newest research showed :
https://www.urotoday.com/video-lectures/advanced-prostate-cancer/video/5413-poseidon-meta-analysis-re-examines-the-role-of-adt-with-salvage-radiation-for-prostate-cancer-amar-kishan.html

Jeff Marchi | @jeffmarc | 6 hours ago

You should definitely get a decipher test. You’ve already had a reoccurrence and you want to find out the chance of Reoccurrence in the future. ArteraAI Is similar and your doctor May prefer that.

The question is how well you were doing on ADT? Are you getting a lot of fatigue? I’ve been on a for eight years and I don’t get fatigue so it’s not really a problem for me. Same things happened to some other people You need to figure out what you can handle. After having a reoccurrence so soon you do want to stay on ADT for 24 months if you can.

You should probably be on an ARPI, Darolutamide Has the least side effects you should ask your doctor about adding that. Normally, when somebody fails their prostatectomy so quickly, they will put them on that or one of the other ARPI drugs.