Adding d-Mannose, stage 3 CRC adenocarcinoma, FOLFOX chemo

@bethcamp - As we discussed previously, D-Mannose is a simple sugar closely related to glucose, naturally found in fruits like cranberries, apples, and peaches. It’s commonly used to support urinary tract health by preventing bacteria from adhering to the bladder and urinary tract walls, potentially reducing infection risk. Some studies suggest D-Mannose may have an inhibitory effect on certain cancer cells, including bladder cancer, by interfering with their growth and adhesion, though research is still preliminary and not conclusive. It’s generally well-tolerated, with minimal side effects for most people, but its impact on masking bladder cancer symptoms isn’t well-documented and would require further investigation
It’s great to hear your oncologist was supportive of your D-Mannose use, especially given the study you mentioned about its potential to inhibit cancer cell growth. It’s understandable to wonder if it might have masked symptoms, as its soothing effect on the bladder could reduce discomfort. Continuing it post-chemo seems like a thoughtful choice, especially since you’ve experienced only positive effects. It’s also helpful to know AZO helps with pain but causes nausea for you—D-Mannose’s gentler profile sounds like a good fit. Have you discussed with your oncologist whether D-Mannose’s benefits might interact with your chemo or affect symptom monitoring? It could be worth exploring to ensure it aligns with your treatment plan.