Ablation Therapy - Does It Lead To Metastases?

Posted by mrscott @mrscott, Oct 4, 2022

In trying to research ablation therapies such as TULSA-PRO, at least one source suggests that ablation leads to circulating tumor cells, which tend to establish micro-metastases?
"Whole gland TULSA-PRO and HIFU outcomes" blog on ProstateCancerNews.

Have I understood this correctly?
Can met establishment be avoided by e.g. ADT treatment? The therapy is appealing as a 'first pass', in terms of low side-effects and not blocking later RT or RP. However if this idea is incorrect, I certainly don't want to follow it...

Interested in more discussions like this? Go to the Prostate Cancer Support Group.

melcanada | @melcanada | Oct 5, 2022

My situation, just get the prostate out by surgery or robotic surgery and get on Zolodex which a stops testosterone the fertilizer of P Cancer

Frinds who did other stuff have since died
After 5 years mine did go to my L2 lunbar which they then radiated and put me back on Zolodex
PSA 1.2 for 2almost 2 years since

FYI stats, seer.cancer.com survival by age race, sex type etc

Colleen Young, Connect Director | @colleenyoung | Oct 15, 2022

@mrscott, you ask a good question and I might suggest asking your cancer team about whether ablation is right for you. Reading evidence-based sources, I have not found evidence that ablation causes spread.

Here are a few articles from Mayo Clinic that I think you'll appreciate:
- Mayo Clinic Q and A: Advances in ablation for prostate cancer https://newsnetwork.mayoclinic.org/discussion/mayo-clinic-q-and-a-advances-in-ablation-for-prostate-cancer/
- High-intensity focused ultrasound for the treatment of prostate cancer https://www.mayoclinic.org/medical-professionals/urology/news/high-intensity-focused-ultrasound-for-the-treatment-of-prostate-cancer/mqc-20519431

Fellow members, like @michael1952 @poodledoc @jamesbyron, are discussing ablation in this related discussion:
– Anyone do Tulsa Pro, newer laser ablation procedure? https://connect.mayoclinic.org/discussion/tulsa-pro/
– Anyone do Tulsa Pro, newer laser ablation procedure? https://connect.mayoclinic.org/discussion/tulsa-pro/