A year on Tymlos . . .

Hi all,

Thought I'd report in, since there's a lot of interest in Tymlos.

I've had osteoporosis for about 25 years, thanks to a hysterectomy at 50. I took Fosamax for about 8 yrs, then went off. I stupidly did nothing for several years, then saw an endocrinologist, who put me on Prolia for three years. I tolerated it well but didn't see any improvement in my bone density scans (spine was the worst, about T score of -3.4 SD). She suggested switching to Tymlos, but the cost put me off.

In Oct 2023 I tripped over the damn vacuum (that'll teach me to clean), had a bad fall, and wound up with a compression fracture at L1. In Jan 2024 I went on Tymlos and have taken it faithfully since then.

I had a DEXA scan yesterday, and my spine has improved to T -2.6, which is fantastic. Everything else stayed pretty much the same, but they were never that bad (e.g., hip still at -2.1 ); for obvious reasons, my spine was the biggest concern. I have other spinal problems, including arthritis, spinal stenosis, and a couple of bulging disks and resultant nerve impingement, so I have pain when I'm on my feet for more than a few minutes, but at least structurally I'm now in a better place.

The plan is to continue Tymlos for another year. Then we'll see. She is a proponent of Prolia, esp now that you can stay on it for much longer than was recommended a few years ago. I'm 78, so I guess she figures why not, if it will prevent deterioration once the Tymlos has done its magic?

Anyway, that's my story. Right now I'm celebrating.