A PSA question: Is 0.7 my nadir (lowest)?

Posted by stew80 @stew80, Jul 26, 2025

I started Eligard in March this year (2025). PSA dropped from 10 to 0.6 a month later. Then in May it crept up to 0.7.
I recently began 20 sessions of EBRT (8 done to date). Had a PSA test this week (now 5 months into ADT). It's still 0.7.
I'm wondering - is this the 'nadir' for me and why doesn't it go to undetectable? I'm 4+5 with no spread beyond one seminal vessel. There is cribriform evident.

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olman | @olman | Jul 28, 2025

This is one reason I asked about the history of PSA.

I now in fact work on making myself less available

stew80 | @stew80 | Jul 28, 2025

At least something is getting up. 🙂

asolidrock | @asolidrock | Jul 31, 2025

My psa was 54. After injection I dropped to 19. So suming is working .

hunnybunnys3 | @hunnybunnys3 | Jul 31, 2025

In reply to @asolidrock "My psa was 54. After injection I dropped to 19. So suming is working ." + (show)

What was the injection? My husband has prostae cancer and his PSA was 38.8, biopsy confirmed cancer with gleason score of 9/10. He received cancer pills everyday for one year and lupron injection for two years. So far, PSA is zero.

asolidrock | @asolidrock | Jul 31, 2025

Does he have metastatic cancer?

hunnybunnys3 | @hunnybunnys3 | Jul 31, 2025

In reply to @asolidrock "Does he have metastatic cancer?" + (show)

No, at least not now, meds still in his system so won’t know for sure for several months

asolidrock | @asolidrock | Jul 31, 2025

Well I'm glad for you because I do;although my urologist said I'd be ok as long as i take my nubeqa and injections every 3 months. I pray for your husband that his doesn't spread. Thanks for your reply

wrangler59 | @wrangler59 | Apr 14 1:04pm

I am so confused about what and where to do here I’ve got info overload I’ve lost ability to get fully erect have difficulty draining bladder feels full even though I’ve just gone urologist has tried all the Ed meds including shots in the penis taken creams and shots for low T and put me on a large dose of Flo max ti no avail I wake up exhausted daily no matter how much sleep my PSA is normals as well as rectal exams I feel an uncomfortable feeling in my pelvis nothing is working tried everything on internet with no results where do I go from here

Jeff Marchi | @jeffmarc | Apr 14 2:14pm

In reply to @wrangler59 "I am so confused about what and where to do here I’ve got info overload I’ve..." + (show)

@wrangler59
Have you had any evidence that you have prostate cancer? Is your PSA elevated? Have you had an MRI?

It sounds like you need to go to a center of excellence that has a urologist and a lot of other doctors to work on your case. You are not having this resolved where you’re at so doing this can make a big difference. If you mention where you live, we could give you a place you can go that’s a center of excellence..

As far as sleep goes. If you are sleeping during the day for more than about 30 minutes, that is what’s causing your problem with fatigue. If you sleep an hour or more, you go into rem sleep during the day. That then prevent you from getting a full night sleep because you’ve already been in rem sleep. Use a timer and make yourself wake up after 30 minutes if you’re sleeping during the day.

This is the prostate cancer forum so finding a center of excellence is some of what can do for you if you do not have prostate cancer. It could be somebody else has a similar experience and can comment.