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300mg Wellbutrin xl to 450mg

Posted by kah869 @kah869, 15 hours ago

My Dr. wants me to go to 450mg to boost my lack of motivation and still some depression issues. I’ve been on 300mg for a year or longer and never had any side effects at all. With that said I’m am really struggling to get myself to take the extra 150mg pill, for the last 7 days I get my 300mg and 150mg ready and stare at them eventually taking my 300 and putting the 150 away telling myself I’ll start tomorrow. I’m extremely nervous about the seizure possibility. I have no other risk factors, never had a seizure, don’t take another meds that would increase my chances, no alcohol or drug use, no eating disorders but I still just can’t get myself to do it. I guess my question is how safe is 450mg? Am I just overthinking this?

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Profile picture for scottbeammeup
scottbeammeup | @scottbeammeup | 13 hours ago

Not a doctor, but I've been taking Wellbutrin for awhile so I researched this because of a similar concern to yours. The odds of a seizure for someone with no previous seizure disorders is 1 in 1,000 for 300 mg and goes to 1 in 250 for 450 mg.

The risk is front-loaded, meaning if a seizure is going to occur it will almost always happen within the first month after starting or increasing the dose. After that, the risk goes way down until, after several months, it becomes almost zero.

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Profile picture for Randy Shields
Randy Shields | @randallshields56 | 10 hours ago

that is a good question, i am not a doctor but myself was bumped up on a drug when in my mind i did not need the increase. i am going to fight it to have it lowered it was increased 25 mg. i hear and see people on this platform that use the same drug with higher mg. but i want off some of these drugs not adding to them. mine is also a seizure med and i take two others for the same reason. have not had a seizure now in months. wish i could give you the answer, myself i am taking like 26 meds a day and think i maybe need half but i am not the doctor and do not see the study on every med i take , wish you luck on your finding an answer, also sending a prayer for you too------------sent. Have a blessed day.

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Randy Shields | @randallshields56 | 5 hours ago
In reply to @randallshields56 "that is a good question, i am not a doctor but myself was bumped up on..." + (show)
Profile picture for Randy Shields @randallshields56

that is a good question, i am not a doctor but myself was bumped up on a drug when in my mind i did not need the increase. i am going to fight it to have it lowered it was increased 25 mg. i hear and see people on this platform that use the same drug with higher mg. but i want off some of these drugs not adding to them. mine is also a seizure med and i take two others for the same reason. have not had a seizure now in months. wish i could give you the answer, myself i am taking like 26 meds a day and think i maybe need half but i am not the doctor and do not see the study on every med i take , wish you luck on your finding an answer, also sending a prayer for you too------------sent. Have a blessed day.

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