M y wife has had BRP for a good 20 years. Tried everything. All kinds of meds for for other diseases that may help with hers. Oddly the best thing for her is Capsacin. I think I misspeleed it. But along with the Capsacin she uses Ebanol- which is a numbing creme. When she told her Dermatologist about what she was using he said to use it if it helps. By the way w live in NJ. So neither cold nor hot weather changes her situation. She had ben to many Dermatologists locally and most referred her to a Dr at NYU Langone. We didnt want to start with a Dr that was a long commute but we stuck with him for 10 years. Since nothing helped she deicided to try the Capsacin with Ebanol. And we quit going to him.