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Anyone on Keytruda experience adrenal dysfunction?

Posted by mpuap @mpuap, Oct 29, 2023

Anyone on Keytruda experience loss of adrenal gland function? If so, what were your initial symptoms? I’m on Keytruda, xeloda and Ivermectin and it’s working well but the keytruda took out my thyroid and now experiencing profound exhaustion while ramping up thyroid dose.

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Moderator
Colleen Young, Connect Director | @colleenyoung | Oct 29, 2023

@mpuap, I added your question to the Prostate Cancer support group as well. If I recall correctly you have “mucin producing urothelial adenocarcinoma of prostate”. I thought you might get additional responses here.

It is tedious and time consuming to get the right thyroid dosage and requires a lot of patience. Along with the profound exhaustion from a dysfunctional thyroid, I bet it is also challenging to distinguish what is related to hormonal imbalance and the fatigue that can accompany cancer and treatment.

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rono2410 | @rono2410 | Oct 31, 2023

Has anyone diagnosed with renal cell carcinoma experienced leg weakness (in my case, the right quad muscle)?

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frlgibson | @frlgibson | Jan 13 7:23am

Yes! I had to stop taking Keytruda after it shut down my adrenals. It also crashed my thyroid. Maybe others aren’t affected, but I was very very sick. I’m better now with hydrocortisone and higher doses of synthroid. It seems to be a pituitary issue and autoimmune problem. I had to completely rebuild my strength. I hope you and others are doing alright.

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1 reply
mpuap | @mpuap | Jan 13 10:44am
In reply to @frlgibson "Yes! I had to stop taking Keytruda after it shut down my adrenals. It also crashed..." + (show)
@frlgibson

Yes! I had to stop taking Keytruda after it shut down my adrenals. It also crashed my thyroid. Maybe others aren’t affected, but I was very very sick. I’m better now with hydrocortisone and higher doses of synthroid. It seems to be a pituitary issue and autoimmune problem. I had to completely rebuild my strength. I hope you and others are doing alright.

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It took out my thyroid but I have ramped up the levothyroxine and doing good in that area. Wondering if anyone has had the high dose IV vitamin C with doxycycline and azithromycin to kill stem cells. Academic studies on this sound promising.

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1 reply
frlgibson | @frlgibson | Jan 17 8:53am
In reply to @mpuap "It took out my thyroid but I have ramped up the levothyroxine and doing good in..." + (show)
@mpuap

It took out my thyroid but I have ramped up the levothyroxine and doing good in that area. Wondering if anyone has had the high dose IV vitamin C with doxycycline and azithromycin to kill stem cells. Academic studies on this sound promising.

Jump to this post

Thanks for your reply! Yes, my thyroid is doing fine. I upped my levothyroxine also. I don't know anything about IV Vit C. I don't understand why you'd want to kill stem cells. I will do some research...

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