@kstar077, @ema1, @enaska1 - Hello ladies! I thought I would chime in with my experience.

I had DCIS; Right Breast; Grade 2; HR/HP positive, >90. I had surgery and Radiation, but I am not taking Aromatase Inhibitors because of their side effects. The decisions we are faced with are daunting and cause a lot of anxiety, don't they? I was initially totally against doing any radiation. But both my radiation oncologist and my family were asking me to reconsider. It was psychologically very challenging!

That's when I decided to rely upon the numbers: I set a maximum of 15-20% reoccurrence. In other words, if tests would indicate that my risk WITHOUT radiation was 15 to 20% for reoccurrence, I would do radiation.

As it turned out, my margins were not clear. Additionally, the test "PreludeDX" indicated a pretty significant recurrence without radiation (15%). I did do radiations because my risk for reoccurrence was at least 15%. In case you don't know about "PreludeDX":

"DCISionRT is a risk assessment test for patients with ductal carcinoma in situ (DCIS). The test was developed by PreludeDx and built on research that began with funding from the National Cancer Institute to better understand the biology of DCIS. DCISionRT assesses a patient’s individual biology along with other risk factors to provide a personalized assessment that predicts the risk of your DCIS coming back (recurring) over the next 10 years. The test calculates a personalized recurrence score and identifies your risk as low or elevated. DCISionRT provides information that may help you and your physician make a more informed treatment decision. "

Based on the results shown by PreludeDX, my oncologists recommended Radiation and Aromatase Inhibitors. I decided to get the radiation; however, I chose not to take AIs.

I did radiation belly-down. This is a way to decrease potential radiation damage to tissue and organs behind the breasts, such as the lungs and heart, if on the left side.

HUGS to all!

D.