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Rising PSA's after treatment - an answer

Prostate Cancer | Last Active: Jan 11 8:59am | Replies (31)

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@consultant

That pretty much sums up the point I was making but I was referring to treatment strategies at much earlier stages. So the paper essentially contradicts what I'm advocating but I still question how solid the data is given very few patients probably did triplet when they were pre-(clinical) metastatic. Regarding certain cohorts of mHSPC patients it states:

"While early, aggressive treatment intensification with triplet regimens, with or without primary radiotherapy, may seem attractive in this cohort of patients to maximize survival outcomes, the reality is that such “maximal” treatment intensification is unnecessary in the majority of these patients."

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Replies to "That pretty much sums up the point I was making but I was referring to treatment..."

I posted to reinforce what you are saying.

Ours is not a homogenous disease. Every scrap of clinical data must be scrutinized when making treatment decision in concert with our medical team.

We also need to understand the significance of terms and their difference, radiographic vs progression free versus overall survival...

Nobody wants to over treat, neither do we want to miss the window of opportunity to impact the course of our cancer by under treating.

I always feel comfortable in my treatment decisions because I believe it is an informed decision, based on my clinical data and in concert with the training, education, experience and support of my medical team.