Hi lowell77,

Just giving my opinion from personal experience. I always first look at what I've been doing over the past 3-4 days. Is there something that I've done that could have caused the stiffness and aches in the wrists/shoulders? One time I was ready to increase my dose until I remembered about helping load and unload some furniture from a pickup truck. I did minimal lifting but it was awkward. I gave myself a couple more days and sure enough, the symptoms were gone. Personally, if I can't find something that I've done that's causing the pain and aches, then I'm looking at increasing my dose to the previous level that was effective. Sometimes a dose might be just a hair low to be effective but it takes a couple weeks for the inflammation to accumulate and make itself known through the pain and discomfort. I don't like to give the pain a head start - I try to catch it early so I don't have to go to a much higher dose so it'll get under control again.