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@retireddoc

I asked by MO at JH (he is the Director of the Brady Urologic Institute which is Hopkins research facility for prostate cancer) what he thought the biggest breakthrough was going to be in the next few years for treatment and he said Pluvicto (LU-177 tagged to PSMA). I am hoping there is a breakthrough in immunologic therapy but so far that doesn't seem to be particularly helpful. There is a new immunologic therapy for metastatic melanoma which apparently results in complete remission in about a quarter of cases (don't quote on numbers), so there is hope for other cancers too.

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Replies to "I asked by MO at JH (he is the Director of the Brady Urologic Institute which..."

Yes, my onco team already talked to me about Pluvicto, just to let me know that there were now options in addition to chemo if/when my (oligo) mCSPC becomes castrate-resistant.

But so far, as long as ADT+Erleada keeps my PSA < 0.01 on the ultra-sensitive test and no new symptoms show up, I'm not going to try to fix what ain't broke. 🙂

I don't love ADT. I miss having body hair, for example (though I still shave), I'm self conscious about the mild gynomastia, I have to work very hard at weight management, and I have a couple of sick-y days every month after my Firmagon injection. Still, I was paraplegic from the tumour at time of diagnosis, spent 3 1/2 months in a hospital bed, and have gradually worked my to reasonably-good mobility over the 2 years since I got discharged, so ADT side-effects seem like minor issues compared to being able to come home, walk again, and just generally get my life back. I can see how it might be different for someone who went from feeling OK straight to the ADT side-effects.