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@retireddoc

Where did you see that? My MO at JH was essentially following the ARASENS trial but he believes there is no supporting data that 6 cycles of Docetaxel is any better than 4. My Darolutamide was discontinued after the chemo (PSA was undetectable). He strongly suggested pelvic radiation as I had a positive node on PSMA PET prior to beginning the triple therapy. My Lupron was discontinued after year with PSA still undetectable.
Was this similar to your treatment? I don't believe there is a set in stone protocol for the triple therapy at this time and trials are underway to assess the best exact protocol.

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Replies to "Where did you see that? My MO at JH was essentially following the ARASENS trial but..."

The information is a compilation of multiple sources including expert webinars and publications. Researchers deterined that 10 cycles is the sweet spot. Researchers then began subtracting cycles to see how many cycles they could reduce to avoid side effects - they agreed on 6 cycles.

All PC is different for each person. I was diagnosed Stage 4 De Novo. The PC went to my bones (i.e., spine, ribs, and pelvis). My doctor thinks a lot like Dr. Kwon. Hit the hell out of the PC up front with triplet therapy. I first was given 10 treatment of radiation to my spin and then 5 to the ribs. I started ADT and Darolutamide and then Chemotherapy. I finished 6 cycles and asked if I could have more. Because I had zero side effect to chemo and my blood was other worldly, and my PSA was dropping too slowly I did 10 cycles. After completing all 10 cycles my PSA dropped to 0.238. My PSA continued to drop post Chemo and is undetectable. For me, I wanted to kill as many micro metastases as possible. That was my choice and my journey. If my doctor would have let me have more cycles I probably would have done 12 cycles in total. I probably will have to continue on ADT and Darolutamide indefinitely. I am determined to live with this cancer and not die of it. I also eat a 70% plant based diet. I work every day and exercise.