Good evening. Welcome to Connect and Happy New Year.
When I read your very recent post while I was browsing this evening, I sat up straight and read it a second time. I could have written that about 18 months ago. That was just before my first injection of Dupixent. After about four years of going through what you have described, I was getting worse and worse. I don't think everyone knows how itching can take over and leave you destroyed, disabled, and particularly exhausted.

One day my dermatologist introduced me to Dupixent for my "neuropathic itch". I knew the worst of the itches was coming from inside my body. We had taken care of some of the atopic dermatitis effects with known ointments, a complete cleansing of bedding, and clothing, and endless applications of light therapy. But the interior itch.....just literally knocked me out. I would be huddled on the floor unable to stay alert or retain my composure.

It took some time to get the Dupixent prescription approved and then the day arrived on August 13, 2022. After the self-injection, I tried to relax and wait for the desired absence of the "itch". Since that day I can honestly say, I have never had to deal with either interior or exterior itch.

However, I did not have CLL so do not know if Dupixent would work the same way for you.
You can call the company and talk to a patient assistant at 844 387-4936 from 8 a.m. to 8 p.m.
It is certainly worth checking out. Please let me know if you need assistance of any kind. I would appreciate hearing about your experience.

May you be safe, protected, and free from inner and outer harm.
Chris