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Ideas for pain relief from Small Fiber Neuropathy (SFN)

Neuropathy | Last Active: Apr 26 7:21pm | Replies (449)

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@joemb

I have severe SFN over the entire body for a good 9 years probably contracted through vitamin deficiencies. The pain is excruciating. I've been on 60mg Duloxetine and 100% pain free. I've even managed to reduce it for 1,5 years to 30mg! It was a life-saver! After that I stopped medication belieiving I was healed only to see it return after six weeks. I started duloxetine again on 60mg and two months ago it all returned. Either my condition got worse or I developed tolerance to duloxetine. I am now additionally on pregabalin but the side effects are terrible. The worst is respiratory depression and enormous fatigue.

I have now started (added) 4x400mg daily of PEA tablets. Fingers crossed this will work. I want to get rid of pregabalin.

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Replies to "I have severe SFN over the entire body for a good 9 years probably contracted through..."

Welcome @joemb, Sorry to hear your neuropathy has gotten worse after you seemed to be doing better. Since you mentioned you started with PEA tablets I thought you might like to take a look at the following discussion:
--- Palmitoylethanolamide (PEA): Anyone had success?: https://connect.mayoclinic.org/discussion/pea-success/

You mentioned that you thought your SFN might be due to vitamin deficiencies. Have you been tested for vitamin deficiencies?