← Return to ET, Polycythemia, Jax2: Is this a blood cancer?

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@nohrt4me

More current knowledge such as ...? I get updates from the MPN Research Foundation and other MPN groups, and I know of no such knowledge afoot. Please do share this more current knowledge!

Classification does not change the way ET works: a spontaneous genetic mutation causes bone marrow to overproduce platelets with abnormal nuclei. Without treatment, platelets can eventually rise high enough to cause clots, cause acquired von Willebrand's, and fibrosis in the marrow that messes with other blood cell levels.

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Replies to "More current knowledge such as ...? I get updates from the MPN Research Foundation and other..."

My comment is an opinion based on conversations I had with hematologists whose credentials I respect soon after receiving my JAK2 bone marrow results. In vet school, we were required to purchase a computer instead of a microscope to start our freshman year so we could learn how to find and evaluate information. We were told that vetting articles published in peer-reviewed journals and books published by academic publishers took so much time that their information could be years old by the time they were issued. When I want the latest information or opinion, I consult directly with the experts.

I am not arguing the pathophysiology of ET. That's basic science of cells and cytology. You (and some organizations) and I disagree on whether to call it "cancer." I've had breast cancer and bilateral mastectomy. I am not afraid of the C-word. I choose to listen to hematologists (my personal doctor and others) who told me adamantly, "You do NOT have cancer. You have a blood disorder." Others in this group have been told the same thing by their doctors. Let's agree to disagree.