← Return to ET, Polycythemia, Jax2: Is this a blood cancer?

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@ontheverge

I find that younger hematologists, perhaps with more current knowledge and data, call ET a "disorder" and disagree with the WHO classification of "cancer".

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Replies to "I find that younger hematologists, perhaps with more current knowledge and data, call ET a "disorder"..."

More current knowledge such as ...? I get updates from the MPN Research Foundation and other MPN groups, and I know of no such knowledge afoot. Please do share this more current knowledge!

Classification does not change the way ET works: a spontaneous genetic mutation causes bone marrow to overproduce platelets with abnormal nuclei. Without treatment, platelets can eventually rise high enough to cause clots, cause acquired von Willebrand's, and fibrosis in the marrow that messes with other blood cell levels.