PRP (platelet rich plasma) injection?

I’m starting PRP therapy next week. This protocol, known as “PET”, consists of three injections, each a week apart. Week one: PRP. Week two: Euflexa. Week three: Toradol. Any experiences here? Thanks.

Mary,
My knee is “bone on bone” with almost no cartilage at all. Did you still have knee cartilage when you started
your PRP injections?

Thank you,

Very little; mine was mostly bone on bone as well.

Mary,
Thank you for your timely response. I had read that PRP is less likely to help in patients who have minimal cartilage. Your positive response to your PRP injections gives me confidence that it can work for me too.

I thought PRP only works on soft tissue. Interested to find out more.

From HSS.edu:
Platelet-rich plasma (PRP) is produced from a person's own blood. It is a concentration of one type of blood cell (platelets), which is critical for blood clotting. This concentration is injected to an injured or diseased part of a person’s body to accelerate the healing of damaged tendons, ligaments, muscles, bones and joints. A key advantage of PRP injections is that they can reduce the need for opioids, or even over-the-counter anti-inflammatory medications. In fact, use of anti-inflammatories should usually be ceased at the time of PRP treatment, because the platelet-rich plasma optimizes the initial inflammatory response involved with healing.

@healthseeker we have a lot of experience with PRP. The only part of what you posted that was a surprise was the inclusion of bone. We were told soft tissue only and imaging was done to make sure that that was what we were dealing with. Perhaps it was limited scope due to studies being done. What is HSS.edu?

I found HSS when I was doing research on Platelet Rich Plasma injections. From their Website:

HSS is nationally ranked No. 1 in orthopedics (for 14 years in a row) and No. 2 in rheumatology by U.S. News & World Report (2023-2024).

Here is their website and article about PRP:
https://www.hss.edu/condition-list_prp-injections.asp

Below is an excerpt from the same website:

PRPs injections are used primarily for soft tissue injuries, such as minor rotator cuff and Achilles tendon tears. Its use in other soft-tissue injuries is becoming more common. It has been demonstrated to improve function and reduce pain in people who have tendonitis or chronic tendinosis conditions such as tennis elbow or golfer's elbow.

It can also be used to treat injuries to ligaments and muscles. For example, improved muscle regeneration has been shown in gastrocnemius (calf) muscle injuries.

Recent data suggests that PRP treatment is superior to than hyaluronic acid injections (also known as viscosupplementation or “gel shots”) for knee osteoarthritis, especially in regard to the duration of its positive effect. However, emerging data demonstrates that PRP combined with hyaluronic acid is more effective than either treatment alone.

I had PRP over 12 years ago when I fell on the ice and tore a ligament in my hip area. It worked wonderfully. Unfortunately, I don't think it is covered by most insurance.