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Can polycythemia cause iron deficiency?

Blood Cancers & Disorders | Last Active: Dec 31, 2023 | Replies (4)

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@loribmt

Good morning, @mdobney Welcome to Mayo Connect. Polycythemia vera is a blood condition where your body is producing too many red blood cells. There can be a couple of potential reasons for this to happen so your doctor may run a few more tests to find the underlying cause.

I’m providing a few links below to informational articles about PV so you can read about the blood condition, possible causes and treatments.
https://www.mayoclinic.org/diseases-conditions/polycythemia-vera/symptoms-causes/syc-20355850
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https://www.verywellhealth.com/polycythemia-vera-disorder-overview-2252550
We also have quite a number of members in the forum who also have been diagnosed with PV. Here is just one of many discussions where members share their experiences. You can also find more by typing in PV in the upper search bar. Don’t hesitate to pop into any conversation to ask questions!

Polycythemia Vera: Just been diagnosed
https://connect.mayoclinic.org/discussion/polycythemia-vera-1/
Your question was whether or not PV can cause iron deficiency. In a word…yes. You may have already gotten the answer in the articles posted above. But here is an excerpt from an article by the National Institute of Health-Pub Med. (Link below)

“Virtually all PV patients are iron deficient at presentation and/or during the course of their disease.”
https://pubmed.ncbi.nlm.nih.gov/30042411/
You mentioned having elevated liver enzymes in a previous blood test. Were you able to find the cause?

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Replies to "Good morning, @mdobney Welcome to Mayo Connect. Polycythemia vera is a blood condition where your body..."

@loribmt thank you for the response. An ultrasound and MRI showed a slightly fatty liver. My gastro believes that was the reason for the the elevated enzymes. I’ve lost about 10 pounds and my enzymes are now in the normal range. She thought losing weight would also help with my slightly elevated cholesterol. However, it increased significantly in the last 6 months. That’s why I am curious about any correlation.