← Return to Low Dose Naltrexone and Neuropathy

Discussion

Low Dose Naltrexone and Neuropathy

Neuropathy | Last Active: Apr 30 8:05pm | Replies (129)

Comment receiving replies
@rawbar533

I've read several articles regarding LDN's effectiveness with neuropathy pain relief. Does anyone have experience trying LDN, or additional information?

Jump to this post


Replies to "I've read several articles regarding LDN's effectiveness with neuropathy pain relief. Does anyone have experience trying..."

I read:
Low-dose naltrexone (LDN) has increased in popularity as a non-opioid medication that may decrease chronic pain symptoms. LDN is most commonly used to treat fibromyalgia, complex regional pain syndrome (CRPS), and painful diabetic neuropathy.

I did not think naltrexone was usable since it was for treating opioid and acholol abuse.

Welcome @rawbar533, I think you'll appreciate the comments and experiences in this related discussion:
- Low Dose Naltrexone and Neuropathy: https://connect.mayoclinic.org/discussion/low-dose-naltrexone-and-neuropathy/

What's your experience with neuropathy? Have you been living with it for long? What helps you?

I have been using it for about 6 weeks. So far, I can't really say it's helped. Evaluating how effective any treatment is for PN has been a problem for me, and others. The effect, if any, is not usually obvious. Furthermore, there are so many other variables (mood, weather, other meds, on and on) that it is nearly impossible to tell, unless the effect "knocked my socks off" which so far, hasn't happened.
Regarding LDN specifically, I have solved the problem of it being expensive when bought through a compounding pharmacy. I get 50 mg tablets, crush and dissolve 2 (100 mg) in 100 cc of water, thus making a 1 mg to 1cc solution. Then, using an inexpensive pipette I bought, I put 4.5 cc in a small glass of water and drink it.
My pain medicine doc told me it may take 6 weeks or so to see an effect. Also, it is somewhat dose dependent, and he finds that if anything, sometimes a smaller dose is more effective. That may explain the 3 mg dose mentioned above.
Anyway, it's not helping me in any meaningful way, so I'm about to give up. I hope others have better results.