Welcome, @philomenacheung. I'm sorry to hear that your wife is having a hard time with chemotherapy and immunotherapy. I suspect the immunotherapy is the culprit for the rashes. That is a know side effect. Is she on pembrolizumab (Keytruda) or another immunotherapy?

Since this discussion's focus is on radiation, would you mind repeating your question in this discussion:
– Cholangiocarcinoma – Bile Duct Cancer – anyone else dealing with this? https://connect.mayoclinic.org/discussion/cholangiocarcinoma-bile-duct-cancer-anyone-else-dealing-with-this/