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@dazlin, for the MGUS labs, were they using serum electrophoresis with immunofixation (SPEP/IFE), 24-hour urine electrophoresis with immununofixation (UPEP/IFE) and serum free light chains (SFLC)? Those three tests are the standard first pass at diagnosing MGUS.
If they did those and you want to share the values or message me personally (can we do that here?), I'm happy to share what I've learned. Of course I can't give medical opinions, but I can share links to articles that are relevant. For instance, there are "stratification" tables published online that list lab values for various levels of risk of progression to MM.
Replies to "@dazlin, for the MGUS labs, were they using serum electrophoresis with immunofixation (SPEP/IFE), 24-hour urine electrophoresis..."
@nancyworld , I do bloodwork only. I did a bone marrow biopsy a few years ago, which showed 4 percent abnormal cells.
My kappa/lamdra light chains varied between 1.75 to 2.00...they have returned to normal level past year. 1.48 this last test. 1.65 is normal range.
I have not had the Bence Jones (urine) test. M-spike was 0.04, and has not been detected on last bloodwork...2 weeks ago.
I used to do bone scans, checking for lesions, but have not been required to do those anymore.
They feel I have been remained remarkably stable, and will follow up in 1 year.
@nancyworld , just got some results from my primary dr...
Albumin. And alpha 1 high,
Beta absolute is low.
I've researched, and says some inflammation, or cancer...maybe liver. Just took labs this morning, so I haven't heard from Dr yet.
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I should always include a reference here so people have a backup for what I've said. Here's an explanation for the above statements:
https://www.myeloma.org/monoclonal-protein-testsI omitted to mention QIg because I haven't had it and hadn't seen it in my reading yet. Good thing I just looked it up again!
Besides these labs for screening for, and evaluating, plasma-related abnormal proteins, doctors may also run labs to check organ status, like calcium (for bone health), BNP and troponin (for heart health), eGFR and creatinine (for kidney health), and so on.