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Orgovyx and Zytiga combined

Prostate Cancer | Last Active: Apr 10 4:20pm | Replies (28)

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@billfarm

Yes I can. Had prostrate removed 12/15/22. Psa 1.8 then 2.3 by march23. Dr put me on zytiga 1000mg and orgovyx 120 mg with10mg prednisone. By April psa was undetectable and remains so thru dec4. Drugs dropped testosterone from450 or so to20something. Goal was less than 50. I chose oral vs shot so I could bail out if side effects were intolerable. My side effects fatigue initially, maybe a bit of joint pain more than normal. Liver enzymes and heart rythum damage most worrysome. Got ekg and echocardiogram for baseline and check every 3 months. No damage to either so far. Not many concurrent users of this combination. Keep posting
this is a rare combo among guys posting here

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Replies to "Yes I can. Had prostrate removed 12/15/22. Psa 1.8 then 2.3 by march23. Dr put me..."

billfarm:
My first PSA after RP was .19 (retested 30 days .18) and I was directed to radiation oncologist who recommended salvage radiation to whole prostate bed and pelvic lymph nodes and 4 mos ADT.
See SPPORT trial.
Just sharing experience.
Best wishes for successful treatment.

I’m checking in to see how you’re doing. How is your PSA?

My doctor wants to put me on Lupron and Zytiga. I’m asking him if we can substitute Orogovyx for Lipton for better testosterone recovery after 2ys and treatment ends. He is being cautious as they are no big studies on the efficacy of the combo.