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JAK2 Mutation - Effects and Questions

Blood Cancers & Disorders | Last Active: Jun 19 5:59am | Replies (303)

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@loribmt

Hi @remo1110 Blood conditions and blood cancers can be confusing. You’ve been diagnosed with Essential Thrombocytosis which is a condition in which your body produces too many platelets. Platetes are crucial in helping your blood to clot if you’re injured. However, if you have too many it can cause clotting to form where you don’t want it to happen such as deep within leg veins, lungs, etc.
You have an acquired gene mutation which is allowing the normal production of cells to not shut off in a timely fashion so the platelets are in an over production mode.
The medication your doctor has you taking will help get that back under control and the aspirin will keep your blood thinner so that you don’t clot as easily.

I’ve found some good reading literature for you that will really help explain what’s happening.
These two articles are a good overview of thrombocytosis:
https://www.mayoclinic.org/diseases-conditions/thrombocytosis/symptoms-causes/syc-20378315
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https://www.verywellhealth.com/thrombocytosis-overview-and-more-5187124
This article goes into more detail about the JAK2 mutation which is part of your diagnosis.
https://www.verywellhealth.com/jak2-mutation-5217909
I hope this is helpful. Are you having any side effects from the Hydroxurea?

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Replies to "Hi @remo1110 Blood conditions and blood cancers can be confusing. You’ve been diagnosed with Essential Thrombocytosis..."

Thank you so much for your response. I plan on reading the articles you provided.
I appreciate your taking the time to respond to me.

Good luck