Honestly, if you told my husband his MDS was back I’m not sure what he would do. That initial chemo just about did him in and took at least 5 months to have any kind of quality of life. Now almost a year out and is remission for the cancer and 100% donor we still live week to week blood work. Not fun for sure. Not many activities since so many other complications came into play. So if it comes back I truly think he would decline treatments. God bless you. Prayers