@mwilson270 I shall assume that you do not have Stage 3 chronic kidney disease as well. Metformin should not be taken at this stage when your eGFR is low. There are diabetic doses of weekly Ozempic that may help. I now take the 2mg for weight loss but no other diabetic medication for the last several years. You may also wish to consider checking with your urologist as well as the endocrinologist.