I recently was prescribed Eliquis at Rochester Mayo in October. I had an initial RX done by the ER for a starting dose sent to the pharmacy closest to my home my not my normal one I use in Rochester. It was never picked up due to my making another trip to the ER for a blood clot in the lungs and an overnight stay in the hospital. They sent me home with another prescription to my normal pharmacy without a hiccup. I picked up the second RX on my way home from the hospital and tried to pickup the other one at the local pharmacy and it was denied by my insurance company thinking it was fraud for 2 RXs in one day. I've changed pharmacy's a couple of times over the years with Mayo with no problems with my doctors writing a new one.