Hello @serious, this is a great question. I have moved your discussion and combined it with a discussion titled, "Prolia and its side effects" https://connect.mayoclinic.org/discussion/prolia-and-its-side-effects/.

You can read through a few members' experiences, including positive ones. @canadiancc share(d) some of your same concerns with the listed side effects and how long they could last. @tiredpup1 and @hsum4 shared their experience and had little to no side effects.

@serious, pinning down what side effects we may have and how long they last is really difficult as everyone processes medications so differently. As you have found, some people have no side effects at all and some have had bad experiences. Have you discussed your concerns about the side-effects with your provider and what your steps would be if you happen to experience the more severe side effects of Prolia?