Supplements
Hello everyone. Has anyone here ever tried any of these supplements like, " Nuphoria ", " Nerve Renew", or R- Alpha-Lipoic-Acid". Would like to see if someone has actual experience with them. Thank you.
Interested in more discussions like this? Go to the Neuropathy Support Group.
@jerryw
Hi,
I think that your question answer the question, about treatments for neuropathy. I have done many different things and for me diet, exercise, and massage (not for wimps), is working. I have great results with: cold laser therapy, Shockwave treatment, myofascial massage, diet. Yoga and exercise. I was an athlete in my youth and use all that I learned, to improve my neuropathy. I also have IVig. I did use supplements, my Bs counts became spectacular!
JFN
Thanks John. Have you ever heard of people using a Spinal Cord/Back Stimulator? I was reading about these on government and few other websites about these having success with SFN and other neuropathies associated pains and sensory feelings. Thanks
Yes. I met a guy who was in the process for diabetic neuropathy. And I was on disability for a couple years because of trauma caused N.
Because this forum thread is about Supplements I am posting this paragraph about Benfotamine which is a vitamin B1 related supplement. On page 1 or 2 of this thread someone said they found it effective for PN. This is available at any vitamin vendor in the USA without a prescription. (SwansonVitamins.com or Vitacost.com)
(from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8139599/ which reviews several other PN treatments)
Developed in late 1950s in Japan, benfotiamine is a synthetic lipid form of thiamin which is used as a treatment option for alcoholic neuropathy, sciatica, and other painful nerve disorders in alternative medicine. The mechanism for pain control is thought to be through increasing intracellular thiamine diphosphate levels, which serves as a cofactor of transketolase; this enzyme inhibits advanced glycation and lipid-oxidation end products, eventually preventing microvascular complications in diabetics [39].
A randomized pilot study was conducted to evaluate the efficacy of benfotiamine in patients with DPN. The study included 40 patients with type 1 and type 2 diabetes with two or more years of neuropathic symptoms. One group received 50 mg of benfotiamine four times daily, and another group received a placebo. The study lasted for three weeks. A neuropathy pain score was used to assess symptoms of polyneuropathy and vibration threshold was used as electrophysiological baseline parameter. The trial concluded a significant improvement in the neuropathic score in the benfotiamine treated group compared to the placebo group. However, no changes were reported in regards to improvements in vibration perception threshold [40]. A double-blind, placebo-controlled, phase-III-study including 165 patients with DPN were assigned to three groups, i.e., benfotiamine 600 mg daily, benfotiamine 300 mg daily and placebo. After six weeks of treatment, the neuropathic symptoms score showed improvement with benfotiamine compared to placebo with more improvement in higher dose group [41].
It is an economical and readily available product and could potentially serve as an adjuvant supplement for restoring normal physiological nerve function in diabetics. It may help with other chronic complications of diabetes due to its presumed mechanism of action.
Hi Jerry @jerryw, There are some discussions on using spinal cord stimulators for neuropathy if you want to learn what others have shared.
--- What's your experience: Boston Scientific Spinal Cord Simulator?: https://connect.mayoclinic.org/discussion/boston-scientific-spinal-cord-simulator/
--- Comparison of Spinal Cord Stimulators from Boston Sci., Nevro: https://connect.mayoclinic.org/discussion/comparison-of-spinal-cord-stimulators-from-boston-sci-nevro/
I take Alpha Lipoic Acid. At first it stopped the pain of peripheral neuropathy, but now the pain has returned. I now wear compression socks and the pain is less frequent and not as severe.
Hello casd57. What kind of neuropathy do you have? Small Fiber, Diabetic, etc.? Thanks Jerry
Not Diabetic...
Prerifal(sp?) Neuropathy is the only thing the Doctor said..
What I feel is my feet are on fire...I feel weakness up to my knees and I feel pain in my arms and hands but not even close to what I can feel in my feet..
Wow. I feel fire in my feet also. Also like they have plaster inside the bottom . And some burning in lower legs. Sometimes cramping in bottom of right foot. Do you still feel like they are making improvement with the supplements? Sounds like Small Fiber Neuropathy.
Yes.... In Feb to July I made progress but I wasn't taking everything I listed above plus what I was taking was wrong... like just "ALA" not R-ALA or RN-ALA ....and was taking other stuff to help blood flow but it was full of fillers that I mentioned above so that made them less effective...
So like I said in the beginning I couldn't hardly mow my lawn before I had to go lay down and grit my teeth through the pain.... Now, we just went to Disney World-Epcot-Universal 11/14 and we walked 8- 10 miles a day with short sit downs... I also noticed the last few months my feet recovered very quickly...
So yes, they are so much better...