ican only say from mu experience i had 1 shot and it caused me a lifetime of heartache. unfortunately i did not research this drug and i will forever be sorry i didn't if you take a certain collegan and b12 along with the right calcium and other supplement it may help. what bothers me so much is these drs hand out these drugs so quickly and without any real knowledge of what they can do. yes. prolia has helped may but the ones it didn't have suffered severly. all these new drugs are great when they work for you but if you have a reaction the conequences can be life changing it is very hard to make a decision about what to take and how to take it pill form infusion or injection all very complicated. i think from reading posts here an endrochrinologist may be right for you